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Epipedobates Tricolor

Transcript: The Poison Size: 2-3 cm Diet - small arthropods, including insects like fruit flies and ants. A high majority is of Pumiliotoxin-containing ants (1). Location - Forests of southwestern Ecuador and northwestern Peru (2). Life Cycle - Eggs hatch and the male frog brings the tadpoles to the water where they grow into adult frogs. Family Tree - Animalia Chordata Amphibians Anura (Frogs) Dendrobatidae (Poisonous Frogs) Epipedobates Tricolor Defensive Weapon - The phantasmal poison frog secretes an alkaloid from its skin. The frog accumulates the alkaloids from the many ants that it eats. It will only produce its poison if fed the right ants in captivity. Frogs that are captured maintain poison levels for years (1). The poison is called epibatidine, named in honor of the frog. If an organism brushes the frog, the poison will be absorbed in through the skin. The LD50 of epibatidine is .4 µg, which is 200x more potent than morphine 1. Saporito, R., Garraffo, H. M., Donnelly, M., Edwards, A., Longino, J., & Daly, J. (2004, May 5). Formicine ants: An arthropod source for the pumiliotoxin alkaloids of dendrobatid poison frogs. Retrieved from 2. Poison frogs: Dendrobatidae - phantasmal poison frog (epipedobates tricolor). (n.d.). Retrieved from 1. Strong, S. (1998, May 1). Altering chemistry: Epibatidine a novel alkaloid. Retrieved from This means that .4 µg is enough to kill 50% of a population (3). Natural History Histrionicotoxin is very similar to epibatidine Phantasmal Poison Frog 1. Daly, J., Secunda, S., Garraffo, H., Spande, T., Wisnieski, A., & Cover, J. (1994, June 6). An uptake system for dietary alkaloids in poison frogs (dendrobatidae). Retrieved from 2. Strong, S. (1998, May 1). Altering chemistry: Epibatidine a novel alkaloid. Retrieved from 3. Louissaint, P. (2008, September 18). Epibatidine: Nature’s pain reliever. Retrieved from Mode of Action (2) (1) Lets learn about this little fella. Epibatidine binds to a neuronal nicotinic receptors in the brain. This desensitizes the receptor from receiving any of the natural ligand, acetyl choline (1). This effectively shuts down the muscle control system and paralyzes the victim, leading to die of asphyxiation. Accidental poisonings of humans are treatable by putting them on a ventilator until the effects of the poison wear off. There is no medical uses of epibatidine, but a compound that was synthesized from it called ABT - 594 is being tested for a pain relieving medicine (1). Epipedobates Tricolor

TriColor Initiatives

Transcript: TriColor Initiatives TCI? Unique Edge?? What is it going to be? TCI Skills and knowledge: What do I know Comprehensive knowledge of both the Salesforce and Mulesoft platforms Deep understanding of how mule cost structures Insight into the mismatch between the services offered and needed Skills and knowledge Clearest Problems Inefficient Use of Resources Service mismatch. Fascinations and passions What am I doing when I am at my happiest? Spending quality time with family, particularly the kids, and going on trips provide a great source of happiness. Fascinations and passions What do my friends and colleagues complain about that I find effortless? Finding solutions to complex problems seems What do other people say I am great at, or comes naturally to me? Ability to make things work, particularly in a technical context. Reputation for being a go-to person when something needs to be done right. Additional passions and interests: Deep passion for the middle class and farmers. Strong aversion to poor service in any context Why now? Rapid Digital Transformation: According to a 2021 report, 88% of IT leaders accelerated their digital transformation initiatives in the wake of the COVID-19 pandemic, And Digital Transformations on an average goes for 5+ years Increasing Demand for Client-centric IT Services: Report from Microsoft found that 96% of customers say customer service is an important factor in their loyalty to a brand. This reinforces the market need for a more client-focused approach in the IT services industry Why now? Regulatory Changes and Business Adaptability: Report from Gartner found that by 2023, 65% of the world’s population will have its personal information covered under modern privacy regulations, up from 10% in 2020. This indicates an increasing need for businesses to comply with complex data privacy regulations Customer Discovery Jobs to be Done Top Problems Solutions Value Proposition Customer Discovery Problems Problems Solutions Solutions Value Proposition TCI addresses the pain-points of complex IT challenges and upskilling, providing efficiency, peace of mind, and increased team competency, Value Proposition by delivering tailored Mulesoft solutions, 24/7 support and on-demand training that differentiate us from traditional IT service providers. Risky Assumptions Delivery Side Client Acquisition Side Current State Risky Assumptions Delivery Side Delivery Client Side Clients Current State Client Acquisition and Retention: I can effectively attract new clients, satisfy their needs with my services, and retain them over the long term. Sales Rep Relationships and Referral Consistency: I can establish strong relationships with Mulesoft sales reps who will consistently refer clients to me. Current State Reputation Building and Competitive Differentiation: I can build a strong reputation among other Mulesoft partners and differentiate my services in a meaningful way. Lean Canvas Lean Canvas First Iteration Stuff Current State V 0.1 V 0.1 Stuff Stuff Talking to people - MOM Tests Reading reports. Talking to Experts OneDay Teachings SF PAMs and AEs The Lean Canvas V 1.0 Overstatement and underperformance of Mulesoft tasks by service providers. Difficulty for service providers in adhering to client procedures and standards. Unexpected rise in the costs of Mulesoft licenses. Heads of Mulesoft verticals within non-IT companies. Senior IT Project Managers overseeing Mulesoft projects. IT leaders in companies undergoing digital transformation. A team committed to fulfilling client requirements while minimizing license costs. My way of working on Mulesoft, the way in which we can deliver what matters keeping the reduced license cost. Thinking in terms of Mulesoft, Not JAVA or SF. Mulesoft license cost optimization strategies provided. Highly competent team aligned with client needs and desires. Unique focus on Mulesoft, unlike other providers who integrate it with Salesforce or JAVA. Client API traffic/license usage. Duration of client retention. Number of clients experimenting with other vendors but returning to our services. Ratio of successfully delivered projects to total projects undertaken. Mulesoft/SF Partner Account Manager and Account Executives. Events Cold Emails + LinkedIn Provision of services. Consultancy offerings. Support through Catalyst. Training programs. Employee remuneration costs. Expenditure on training and certification programs. Costs associated with internal projects. Expenses related to employee welfare and satisfaction Great IT services The best IT Services Provider Initiatives Ton of Great Executions Enhanced Farmer Income Enhanced Middle Class standards . . . . . A better and a more sustainable world

Background Presentation

Transcript: 14th Week Consulting interns can be expensive Time and Money Personal Experience Preliminary Design Stage NFPA 101 and NFPA 13 New and Existing Education, Business, and Mercantile Definition of Project This app would be used to provide interns and recent graduates with an outline of guidelines for how to design and review designs of specific occupancies. With the given time frame, I will be writing the information that will go into the app Begin parametric study: Speak with my mentor and Jason to understand more about what critical variables I could concentrate on for this app. Choose those parameters and begin my study Gather information from NFPA 101 and NFPA 13 for new and existing education, business, and mercantile occupancies. By: Breanne Thompson Next Steps (Continued) Finish preparing for Draft of Analysis Pull together and discuss results of project Draw my conclusions and state future work needed Turn in Final Paper! 10th and 11th Week Turn in my parametric study Begin draft of analysis Map out the process of the app for the key elements 15th Week References Next Steps 7th Week Prepare for Final Presentation Summarize my draft of analysis into presentation Work on how to incorporate a live demonstration for my presentation App Development Background Information 8th-9th Week Continuous Process Objective-C for Apple products Java for Android products 6 months of studying Places to Learn: Codecademy, iOS Dev Center, Android Developers Training Hire App Developer will cost thousands Prepare Final Paper Dive into Shark Tank! 1. 2. 6th Week Background Presentation 12th-13th Week

Background Presentation

Transcript: Real action and accountability Amnesty International Non-state actors/ Rebel Groups?? ...and what about men?? ignoring male rape victims? would rape exist without a man? Weapons of War: Rape UN as an Arena - NGO's - Discussion and dialogue Arena Instrument Actor Critical Thinking Weapons of War: Rape UN as an instrument UNSC Resolution 1820 (2008) UN as an Actor - UN Action Against Sexual Violence in Conflict Weapons of War: Rape Problems with 1820 "Roles and Functions of International Organizations" "Sexual violence, when used as a tactic of war in order to deliberately target civilians or as a part of a widespread or systematic attack against civilian populations, can significantly exacerbate situations of armed conflict and may impede the restoration of international peace and security… effective steps to prevent and respond to such acts of sexual violence can significantly contribute to the maintenance of international peace and security" (UNSC Resolution 1820, p. 2)" Background Presentation- Kristin Mann Weapons of War: Rape Brief Insight - used to manipulate social control - destabilize communities - weaken ethnic groups and identities Examples: - Sudanese Militia - Rwanda Genocide - DRC Critical Thinking Critical Thinking Increased Data Collection by international organizations - determine humanitarian responses - ensures justice and reparation - provides recognition and dignity

tricolor de paine

Transcript: past continuos the nights Lyrics Lyrics Once upon a younger year When all our shadows disappeared The animals inside came out to ___ Went face to face with all our fears Learned our lessons through the ____ Made memories we knew would never fade One day my father—he told me "Son, don't let it slip away" He took me in his arms, I heard him say "When you get older Your wild heart will live ___ younger days Think of me if ever you're afraid" He said, "One day you'll leave this world behind So, live a life you will remember" My father told me when I was just a child "These are the nights that never die" My father told me , "When thunder ____ start pouring down Light a fire they can't put out Carve your name into those shining stars" He said, "Go _____far beyond the shores Don't forsake this life of yours I'll guide you home no matter where you are" One day my father—he told me "Son, don't let it slip away" When I was just a kid I heard him say "When you get ____ Your wild heart will live for younger days Think of me if ever you're afraid" He said, "One day you'll leave this world behind So, live a life you will remember" My father told me when I was just a child "These are the nights that never die" My father told me These are the nights that never die" My father told me My father told me vocabulary 1.Slip away: a synonym of this word is get away 2. You are afraid: a synonym of this word is startled 3.Behind: a synonym of this word is back 4.Told me: a similar word would be comunicate me 5.Beyond: a synonym of this word is further, farther the nights IN DEPTH https://youtu.beUtF6Jej8yb4 Past continuous tense, also known as past progressive tense, refers to a continuous action or state that was occurring at some point in the past. The past continuous tense is formed by combining the past tense of to be Name DATE DATE

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