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Transcript: Vogue Roll up to Marisa Bartolucci's Magical Mystery Career Tour I learned the craft of magazine writing, editing, and styling at Vogue. Anna Wintour, then creative director, was a mentor. Issy Blow and André Leon Talley were my office mates. André was slim back then!

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Transcript: TIMELINE Manuel Reyes Polanco the birth 1999 1999 the San Fernando valley sylmar ca Place school in the valley 2004 2009 2010 living away one more year middle school issues 2014 2014 clubs graduated 2018 NOW FUTURE

Manufacturing Presentation

Transcript: F3 INTRODUCTION ISO 9001 QUALITY CONTROL STANDARDS IN PRODUCUTION ISO 14001 ENVIRONMENTAL CONTROL STANDARDS IN PRODUCTION ISO 9000 - 1987 ISO 9000 - 1994 ISO 9001 - 2000 ISO 9001 - 2008 ISO 14001 - 1996 ISO 14001 - 2004 ISO 14001 & EMAS -2010 WHAT IS IT? ADVANTAGES ISO 9001 1.Promotes international trade 2.Enhances customer satisfaction 3.Recognized in industry 4.Links up individual process to a system model This gives control over the combination and interaction of the processes 5.Improves employee motivation, awareness, and morale 6.Reduces waste and increases productivity ISO 14001 1.Positive effect on the environment 2.Industry Recognision 3.Operating costs can be reduced 4. Certification in one country covers global operations. 5.Improved public image (eco-friendly) 6.Can provide a competitive advantage 7.The standards have a flexible approach as to how you implement them so you can choose the right way for the type of results you want (target market specific) ISO 9001 Quick outdating of certifications Administration costs Too focused on customer satisfaction with no regard for other stakeholders? Many companies have a already have a quality management system Does Certification mean quality? Does the cost of putting the system in place outweigh the added value to the company? All part of a ‘management fad’? ISO 14001 Become Outdated very fast You could terminate the EMS actions after obtaining the certificate The standard does not require active participation of all staff members perhaps reducing the positive sharing of the objectives Focus is on documentation and data gathering for audits, rather than on activities and actions Stakeholder Transparency ISO 14001s environmental standards are not accepted as high enough by many organisations in the environmental community. IMPLEMENTATION CONSIDERATIONS FOR ISO9001... COST TIME BUREACRACY MAINTAINING FOR ISO 14001 THEY ARE SIMILAR.. COST TIME MAINTAINING PERCEPTION INDUSTRY EXAMPLES ISO 9001 EXAMPLES Who is certified? Dunlop Oil and Marine Ltd. Edgetech Electroimpact Hunting PLC Spacelabs UK City Councils BRITISH GAS • £1M in improved services • £0.5M in work • £1.4 in duplicate visits ISO 14001 EXAMPLES Who is certified? Ford Motor Company Sony Duracell Sharp Fuji HAMMER STORAGE Improved efficiency • Understanding of environmental implications • Clearly defined goals and objectives • Improved relations with customers and suppliers • CO2 emissions cut by 33% • Packaging reduced by 65% SUMMARY BOTH ISO 9001 AND 14001 CAN BE USEFUL FOR BUSINESSES IF THEY ARE IMPLIMENTED FOR THE RIGHT REASONS. STANDARDS SHOULD ALWAYS BE REVIEWED WITH THE OUTLOOK OF CONTINUOUS IMPROVEMENT RATHER THAN AN APPROACH OF ACHIEVING CERTIFICATION AND STOPPING. NOW WE WILL HAVE A DEMONSTRATION OF HOW ISO STANDARDS HELP BUSINESSES ENJOY :) TEAM DISADVANTAGES ISO 9001 Cycle ISO 9001 & ISO 14001

Manufacturing Presentation

Transcript: General Considerations in Solid-State Welding In most cases, metallurgic bonds are created with little or no melting of the base material To Metellurgically bond two similar or dissimilar metals you need: It is important to realize that for a sucessful weld both metal surfaces need to be very, very clean Solid State-Welding Processes Forge Welding Date from about 1000 BCE Forge Welding is a welding process in which the seperate components are heated to a hot working temperature Then forged together by hammers or other means Considerable skill is required of the craftsman in order to achieve welds which stand up to todays standards Not of major commerical importance anymore Cold Welding High Pressure is applied between clean contacting surfaces at Room Temp Needs to be exceptionally clean Both Materials are preferably ductile and free of work Hardening THe compression forces involved may reduce the thickness of the work material by 50 percent Forces may be applied by hand for small parts or power presses for larger ones May cause localized plastic deformation No heat is applied however the temperature of the work piece may rise due to deformation Applications include electrical connections Roll Welding (ROW) ROW Metals are ductile Metals Copper, Aluminum, Low carbon steel, nickel Thickness reduction: Greater than 60 first roll ROW Applications Hot Pressure Welding (HPW) Heat and pressure sufficient to cause coalescence of metals Deformation: disrupts surface oxide film leaving clean metal Carried out in Vacuum Chamber HPW Advantages and Limitations Advantages Simple process Simple joint preparation Relatively low cost equipment Quick weld production High quality joints No filler metal needed Minimally skilled operators required Limitations Not all metals are weldable Not easily automated Length of cycle dependent on time for heating Removal of flash and bulge required after welding HPW Applications Diffusion Welding (DFW) Application of heat and pressure with time for diffusion and coalescence to occur Controlled atmosphere Temperature: Well below metal melting point Plastic deformation minimal Migration of atoms across interface due to concentration gradients DFW Advantages and Limitations Advantages: Dissimilar materials welds are possible Produces a product finished to size and causes minimal deformation Presents less shrinkage and stresses compared to other welding processes Highly automated process does not need skillful workforce Limitations: Costly equipment especially for large weldments Costly preparation with smooth surface finish and exceptional cleanliness Protective atmosphere or vacuum required Long time to completion (+1 hr) Not suited to high production rates Explosion Welding (EXW) Rapid coalescence of 2 metallic surfaces caused by energy of detonated explosive 2 dissimilar metals, clad one metal on top of base metal No filler, no external heat Application Production of corrosion-resistant sheet and plate stock for chemical and petroleum industries Friction Welding (FRW) Friction is induced by mechanical rubbing between the two surfaces, usually by rotation of one part relative to the other, to raise the temperature at the joint interface to the hot working range for the metals involved The parts are then driven toward each other with sufficient force to form a metallurgical bond Axial compression force upsets the parts and a flash is produced by the displaced material The flash must be trimmed to provide a smooth surface in the weld region No filler metal, flux, or shielding gases are normally used Nearly all FRW operations use rotation to develop the frictional heat for welding 2 principal drive systems: - Continuous-drive friction welding - Inertia friction welding Continuous-drive Friction Welding Inertia Friction Welding Rotating part connected to a flywheel which is brought up to a predetermined speed Flywheel is disengaged from drive motor and parts are forced together The kinetic energy in the flywheel is turned into friction heat causing coalescence at the two surfaces Typically takes around 20 seconds to complete Machines used for friction welding resemble engine lathes Require a powered spindle to turn one part at a high speed and a means of applying an axial force between the rotating and stationary parts Since cycle processes are short, useful in mass production The rotating tool consists of a cylindrical shoulder and a smaller probe projection underneath it The shoulder rubs against the top surfaces of the two parts, developing much of the friction heat The probe generates additional heat by mechanically mixing the metal along the butt surfaces The probe has a geometry designed to facilitate the mixing action The heat produced by the combination of friction and mixing does not melt the metal, but softens it to a highly plastic state The probe forces the metal around it, developing forces that forge the metal into a weld seam Advantages - Good mechanical properties - Avoidance

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Transcript: 1860 http://www.uihealthcare.com/topics/medicaldepartments/neurology/huntingtonsdisease/overview.html Charles Davenport Dementia that gets worse Disorientation Loss of judgement Loss of memory Personality changes Speech changes Additional symptoms Anxiety, stress, tension Symptoms in children Rigidity Slow movements Tremors So what do you think this repeat would do to gene function? 1911 Transcriptional dysregulation Protein misfolding and degradation Impairment in intracellular transport, mitochondrial function and synaptic transmission. http://www.stanford.edu/group/hopes/cgi-bin/wordpress/2010/06/the-cognitive-symptoms-of-huntingtons-disease/ Post translational modification-acetyl tag signal SirT1 inhibition, Selisistat Phosphodiesterases inhibitors: PDE 10 and 4 now in testing Gene silencing Stem cell generation of neurons Bruproprion Manipulation of synaptic activity - Memantine Ch Implications of HD http://atlasfolding.com/?page_id=51 Current Therapies https:///nm/journal/v10/n7s/full/,DanaInfo=www.nature.com+nm1066.html Genetic Testing Why Test Mid Stage 1872 Works Cited Amber Johnson, Hannah Killian, Sarah Tamura https://www.stanford.edu/group/hopes/cgi-bin/wordpress/2010/06/the-inheritance-of-huntingtons-disease-text-and-audio/ Basic Symptoms http://schoolworkhelper.net/huntingtons-disease-causes-symptoms-testing/ Mood changes Movement changes Cognition changes Two Forms Huntington's Disease Alzheimer's disease Parkinson's disease Amyotrophic lateral sclerosis (ALS) Prion diseases (CJD kuru etc.) Lose ability to speak and respond Chorea Lose ability to work, drive, perform activities of daily living Difficulties with balance and motor tasks Difficulties with processing information Irritability, aggression, depression Can be done safely More serious than a simple blood test Challenging psychological and social aspects Genetic Information Non-discrimination Act (May 21st 2008) Medical Value? Testing of Minors Anonymous Testing Testing of individuals at 25% risk 1846 Over 80 testing centers nation wide Emotional and ethical issues that come with HD diagnosis - no treatment to delay onset of HD symptoms, cannot cure HD Psychological support is very important ~ 10-20% of people at risk for HD request testing Grade 0: appears indistinguishable from normal brains after gross examination. Grade 1: shows atrophy in the tail, and in some cases the body, of the caudate nucleus. Grade 2: is associated with striatal atrophy that is more pronounced than that detected in grade 1 brains. Grade 3 displays severe striatal atrophy. Grade 4 includes HD cases with severe atrophy of the striatum and up to 95% neuronal Confirmatory/Diagnostic Testing Predictive Testing Prenatal Testing Grading Based on pattern of Striatal Degeneration Stages 1-2 http://www.nature.com/nrn/journal/v5/n5/fig_tab/nrn1386_F1.html Huntington's vs. Neurodegenerative Diseases Adult-onset : most common ages 30 to 50 Early-onset: small number of cases Worsen in 10-25 year period 1 in every 10,000 Americans has HD and more than 250,000 are at risk Most common hereditary disease Behavior Behavioral disturbances Hallucinations Irritability Moodiness Restlessness or fidgeting Paranoia Psychosis Abnormal movements Facial movements Head turning Jerking movements of arms, legs, face etc Slow uncontrolled movements http://www.cumc.columbia.edu/psjournal/sites/juno.cumc.columbia.edu.psjournal/files/Huntington.jpg Johan Christian Lund Dr. Huntington Late Stage Ambrose, C. M.; Duyao, M. P.; Barnes, G.; Bates, G. P.; Lin, C. S.; Srinidhi, J.; Baxendale, S.; Hummerich, H.; Lehrach, H.; Altherr, M.; Wasmuth, J.; Buckler, A.; Church, D.; Housman, D.; Berks, M.; Micklem, G.; Durbin, R.; Dodge, A.; Read, A.; Gusella, J.; MacDonald, M. E. "Structure and expression of the Huntington's disease gene: evidence against simple inactivation due to an expanded CAG repeat". Somatic Cell & Molecular Genetics; 1994, 20: 27-38. Conforti, P., Camnasio, S., Mutti, C., Valenza, M., Thompson, M., Fossale, E., . . . Cattaneo, E. (2013). Lack of huntingtin promotes neural stem cells differentiation into glial cells while neurons expressing huntingtin with expanded polyglutamine tracts undergo cell death. Neurobiology of Disease, 50, 160-170. doi: 10.1016/j.nbd.2012.10.015 Giampà, C., Laurenti, D., Anzilotti, S., Bernardi, G., Menniti, F. S., & Fusco, F. R. (2010). Inhibition of the striatal specific phosphodiesterase PDE10A ameliorates striatal and cortical pathology in R6/2 mouse model of huntington's disease. PloS One, 5(10), e13417. Gil, J. M., & Rego, A. C. (2008). Mechanisms of neurodegeneration in Huntington’s disease. European Journal of Neuroscience, 27(11), 2803-2820. Graul, A. I., & Prous, J. R. (2005). Executive summary: nicotine addiction. Drugs of Today, 41(6), 419. Ho, L. W.; Carmichael, J; Swartz J; Wyttenbach A; Rankin J; Rubinsztein DC. "The molecular biology of Huntington's disease." Psychologocial Medicine; 2001, 31(1): 3-14. Huntington’s Outreach Project for

HD Presentation

Transcript: High Definition -It has a higher resolution than traditional tv's. -the top of the digital television. -High Definition TV/CPU can display images and videos with a higher quality than those found in a standard television. -The difference between SD and HD is that its better quality. But thats only if your computer or Tv/CPU can handle it. -HD you get much more of the experience out of the movie. -Sd is the still the most prominent format for televisions and standard computers. This means that the TV/ Computer you are buying is ready to display at a High definition signal right out of the box. Pixils An Example: HD CPU 30 -Standard definition - It is also cheaper than a HD TV or Computer. - The pixils for SD is lower than its comparision. S.D. ? What is HD? Whats Different about HD than Standard ? SD Wowing template. Click through in 20 steps. High Def Televisons Videos Here is something small... But we can move beyond the present. Why?

Manufacturing Presentation

Transcript: Manufacturing Processes Presentation By:Arbin Karim My Item and the Stock Item & Stock The item that I chose is a drone. The stock that is used to make a drone is Carbon Fiber, plastic, and aluminum https://www.linkedin.com Pictures Pictures Cost Cost The cost of all the material to make a single drone costs around $150 $60 per lb of carbon fiber $.82 per lb of plastic $1 per lb of aluminum Pictures Pictures <img src="data:image/jpeg;base64,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 Manufacturing Processes Processes The three manufacturing processes used to make a drone is machining, joining, and addititve manufacturing. and additive manufacturing is 3d printing. https://youtu.be/6AJoXSq0B3w?t=30 https://www.jouav.com Machining: (using machines to cut or grind material away to make a part For machinging it uses milling to make a drone Machining Joining Additive manufaturing Price Final Price Once the drone has been assembled and everthing works correctly a basic drone costs around $200 Automation makes the price decrease because it work take more time and labor to make it by hand, which makes the price go up.

HD Presentation

Transcript: Now that it's built, let's market it! Join our Client Family! (Asynchronous JavaScript and XML) Spreading the Word (Social Media) (Content Management System) Enhanced User Experience Interactivity Compliant Code (Email Marketing) (Hypertext Markup Language) Custom Development Search-Engine Friendly What's the formula for a successful website? (Cascading Stylesheets) (Extensible Markup Language) Event Sharing Editing Capabilities Your Local Web Development Company Detailed Style (Java Script) Solid Basics (Really Simple Syndication) Social Interaction (Internet Calendar) (Search Engine Optimization) (Uniform (or Universal) Resource Locator) (World Wide Web Consortium) Reaching Your Audience Third Party Integrations Your Place on the Web (ColdFusion) Great Design Martinsville Danville Now Serving: ...and the rest of the world.

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