You're about to create your best presentation ever

Presentation Background Hd Gears

Create your presentation by reusing one of our great community templates.

Gears Presentation

Transcript: Worm and wheel The Simple Gear Train with Idler is basically EXACTLY like the Simple Gear Train except instead of two gears there are three. The third gear is called an idler. There ya go! It's like the two gears are a couple and the idler is the third wheel! *class looks at me with death stare* Hey I'm trying to make this fun okay?! I'm bored out of my mind too! *storms off to next slide again* The Simple Gear Train is simple. Well, how it works is pretty simple. All you have to do is turn the crank to make the gears move and there you go. You have yourself a gear train. Where do you find it? Well the gear train is used where there's a large distance to be covered between the input shaft and the output shaft. Yeah, you see me using vocab. Skillz. By - NeVaeh Washington Simple Gear Train Okay so the Worm and Wheel is another level of difficulty. I guess you could say that it's on the easy-but-not-SO-easy level. Simple Gear Train with Idler Gears Presentation What is this Presentation about? Okay *sighhhhhhhhh* this presentation is basically just me telling you about the builds we made in Mr. Coach Register's class. In this prezi, I chose to talk about the Simple Gear Train, Simple Gear Train with Idler, the Worm and Wheel, the Leadscrew, the Crank and Slider, the Bevel Gear, and finally, the Belt Drive. *hears long, exaggerated sigh from crowd*. Hey! I don't want to do this either but it's a grade so be quiet and let me talk, hmph! *storms off to next slide* add logo here

Gears! Gears! Gears!

Transcript: Team Captain: Hannah Preaus Critical Thinking The Process After following the instructions, we built our first robot! Collaboration within our team Engineer: Lindsie Bostrom Our Team! Robotics in the Classroom Back to the drawing board! The Pre-K Programmers Our team finally accomplished building a robot that functioned for competition. The goal was to get to the finish line the fastest. After lots of team work, problem solving, creative and critical thinking, and gaining an understanding of how robotics and the gears work, we were able to finish and win the final competition! "What could we change?" Hannah made a comment that summed up the feelings of the whole group when she said, "After I left class this week and got in my car, I thought building the robot was complicated. I can't imagine what went into building my car!" Reporter: Lacy Wycoff Artisan: Virginia Dobbins When it was possible, the team captain, engineer, and artisan divided duties and built pieces separately and combined them to check compatibility. "If the gears aren't moving, the robot isn't moving!" After deciding which team member would play each role, we decided on a gears kit named Giggles. We found all of the pieces needed to build our robot and followed all of the instructions in the booklet. After the modifications failed, we decided to start from scratch with a different model named Chompers. We picked Chompers because we could tell that this robot could move forward and backward and would serve us better in the competition. During the build, our team asked questions and helped one another through the process. At one point while building our second robot, Hannah asked Lindsie, "Can you help me get back to step 1? I feel like we missed an entire step." Adaptations to Robot No. 2 We added a set of wheels hoping for forward motion The Pre-K Programmers The Gears! Gears! Gears! Wacky Wigglers Building Set is a gears robotic system created to develop creativity and imagination in children ages 5 and up. The kit comes with instructions and parts to build four silly creatures that operate off batteries and a remote control. Unfortunately, we discovered some issues with our first robot so we sat down to do some problem solving. We were building a robot that would need to be able to compete in a challenge against another robot. Once all of our pieces were together, we discovered that our robot danced in circles and would not be able to cross a finish line. We needed to modify the robot to make it roll forward and to gain speed. Final Thoughts of the Team Gears! Gears! Gears! Robot No. 1 We couldn't believe the thought and detail that went into building an early childhood/elementary level robot. We learned that following step by step instructions isn't enough. Working together, being creative, and willing to make changes is what lead to our success as a team. Chompers before modifications Chompers was top heavy! We had to get creative and remove Chomper's chompers in order to keep it upright. The Competition! The Product Jobs Making some modifications Collaborating with the opponents Chompers after modifications

HD Presentation

Transcript: 1860 http://www.uihealthcare.com/topics/medicaldepartments/neurology/huntingtonsdisease/overview.html Charles Davenport Dementia that gets worse Disorientation Loss of judgement Loss of memory Personality changes Speech changes Additional symptoms Anxiety, stress, tension Symptoms in children Rigidity Slow movements Tremors So what do you think this repeat would do to gene function? 1911 Transcriptional dysregulation Protein misfolding and degradation Impairment in intracellular transport, mitochondrial function and synaptic transmission. http://www.stanford.edu/group/hopes/cgi-bin/wordpress/2010/06/the-cognitive-symptoms-of-huntingtons-disease/ Post translational modification-acetyl tag signal SirT1 inhibition, Selisistat Phosphodiesterases inhibitors: PDE 10 and 4 now in testing Gene silencing Stem cell generation of neurons Bruproprion Manipulation of synaptic activity - Memantine Ch Implications of HD http://atlasfolding.com/?page_id=51 Current Therapies https:///nm/journal/v10/n7s/full/,DanaInfo=www.nature.com+nm1066.html Genetic Testing Why Test Mid Stage 1872 Works Cited Amber Johnson, Hannah Killian, Sarah Tamura https://www.stanford.edu/group/hopes/cgi-bin/wordpress/2010/06/the-inheritance-of-huntingtons-disease-text-and-audio/ Basic Symptoms http://schoolworkhelper.net/huntingtons-disease-causes-symptoms-testing/ Mood changes Movement changes Cognition changes Two Forms Huntington's Disease Alzheimer's disease Parkinson's disease Amyotrophic lateral sclerosis (ALS) Prion diseases (CJD kuru etc.) Lose ability to speak and respond Chorea Lose ability to work, drive, perform activities of daily living Difficulties with balance and motor tasks Difficulties with processing information Irritability, aggression, depression Can be done safely More serious than a simple blood test Challenging psychological and social aspects Genetic Information Non-discrimination Act (May 21st 2008) Medical Value? Testing of Minors Anonymous Testing Testing of individuals at 25% risk 1846 Over 80 testing centers nation wide Emotional and ethical issues that come with HD diagnosis - no treatment to delay onset of HD symptoms, cannot cure HD Psychological support is very important ~ 10-20% of people at risk for HD request testing Grade 0: appears indistinguishable from normal brains after gross examination. Grade 1: shows atrophy in the tail, and in some cases the body, of the caudate nucleus. Grade 2: is associated with striatal atrophy that is more pronounced than that detected in grade 1 brains. Grade 3 displays severe striatal atrophy. Grade 4 includes HD cases with severe atrophy of the striatum and up to 95% neuronal Confirmatory/Diagnostic Testing Predictive Testing Prenatal Testing Grading Based on pattern of Striatal Degeneration Stages 1-2 http://www.nature.com/nrn/journal/v5/n5/fig_tab/nrn1386_F1.html Huntington's vs. Neurodegenerative Diseases Adult-onset : most common ages 30 to 50 Early-onset: small number of cases Worsen in 10-25 year period 1 in every 10,000 Americans has HD and more than 250,000 are at risk Most common hereditary disease Behavior Behavioral disturbances Hallucinations Irritability Moodiness Restlessness or fidgeting Paranoia Psychosis Abnormal movements Facial movements Head turning Jerking movements of arms, legs, face etc Slow uncontrolled movements http://www.cumc.columbia.edu/psjournal/sites/juno.cumc.columbia.edu.psjournal/files/Huntington.jpg Johan Christian Lund Dr. Huntington Late Stage Ambrose, C. M.; Duyao, M. P.; Barnes, G.; Bates, G. P.; Lin, C. S.; Srinidhi, J.; Baxendale, S.; Hummerich, H.; Lehrach, H.; Altherr, M.; Wasmuth, J.; Buckler, A.; Church, D.; Housman, D.; Berks, M.; Micklem, G.; Durbin, R.; Dodge, A.; Read, A.; Gusella, J.; MacDonald, M. E. "Structure and expression of the Huntington's disease gene: evidence against simple inactivation due to an expanded CAG repeat". Somatic Cell & Molecular Genetics; 1994, 20: 27-38. Conforti, P., Camnasio, S., Mutti, C., Valenza, M., Thompson, M., Fossale, E., . . . Cattaneo, E. (2013). Lack of huntingtin promotes neural stem cells differentiation into glial cells while neurons expressing huntingtin with expanded polyglutamine tracts undergo cell death. Neurobiology of Disease, 50, 160-170. doi: 10.1016/j.nbd.2012.10.015 Giampà, C., Laurenti, D., Anzilotti, S., Bernardi, G., Menniti, F. S., & Fusco, F. R. (2010). Inhibition of the striatal specific phosphodiesterase PDE10A ameliorates striatal and cortical pathology in R6/2 mouse model of huntington's disease. PloS One, 5(10), e13417. Gil, J. M., & Rego, A. C. (2008). Mechanisms of neurodegeneration in Huntington’s disease. European Journal of Neuroscience, 27(11), 2803-2820. Graul, A. I., & Prous, J. R. (2005). Executive summary: nicotine addiction. Drugs of Today, 41(6), 419. Ho, L. W.; Carmichael, J; Swartz J; Wyttenbach A; Rankin J; Rubinsztein DC. "The molecular biology of Huntington's disease." Psychologocial Medicine; 2001, 31(1): 3-14. Huntington’s Outreach Project for

Now you can make any subject more engaging and memorable