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Transcript: Leukemia starts in the tissue that forms blood.The cells don't die when they should, so they crowd out normal white and red blood cells, making it hard for them to do their work. There are four main types of Leukemia: Chronic lymphocytic leukemia Chronic myeloid leukemia Acute lymphocytic leukemia Acute myeloid leukemia CLL Affects lymphoid cells Mainly grows slowly 15,000 new cases each year Affects people over age 55 CML Affects myeloid cells Usually grows slowly at first 5,000 new cases each year Mainly affects adults ALL Affects lymphoid cells Grows quickly 5,000 new cases a year Most common among children but also found in adults AML Affects myeloid cells Grows quickly 13,000 new cases a year Occurs in both adults and children No one knows the exact cause of leukemia, but some possible risk factors are: Radiation Smoking Benzene Chemotherapy Down syndrome Genetics and certain blood disorders Symptoms: Swollen lymph nodes Fevers or night sweats Infections Fatigue, feeling weakness Bleeding & bruising easily Swelling in the abdomen Weight loss Pain in the bones and joints Treatment Options: Usually requires urgent treatment to reduce symptoms and get blood counts back to normal. Treatments are usually chemotherapy and drugs. Some new treatment approaches include using fludarabine combinations and monoclonal antibody-targeted therapy. Some ways to decrease your chances of getting leukemia: Don't smoke Stay away from radiation How Leukemia is Diagnosed: Physical Exam: A doctor will look for lumps or abnormalities Blood Tests: CBC or complete blood count which counts the numbers of red and white cells and platelets Biopsy: bone marrow aspiration is used to diagnose leukemia Spinal Tap: Fluid is taken from the spine and examined for cancer Works Cited: A cancer of the blood L Leukemia


Transcript: Leukemia Leukemia is a form of cancer that affects blood forming tissue in the body. It occurs when white blood cells (WBC) start to replicate uncontrollably, eventually crowding the normal functioning cells around them (WBC, RBC, and Platelets). This causes the normal cells to stop functioning,. The leukemia cells are located in blood forming tissue, but mainly in the lymphatic system and bone marrow. Common Types of Leukemia: •Chronic lymphocytic leukemia(mainly adults) •Chronic myeloid leukemia (mainly adults) •Acute lymphocytic leukemia (mainly adults) •Acute myeloid leukemia (adults and children) Symptoms fatigue shortness of breath night sweats bruising aching bones/joints mild fever paleness of skin Tests & Diagnosis Complete Blood Count Test: counts WBC, RBC, and platelets in sample. If high WBC, and low RBC, it indicates leukemia Bone Marrow Biopsy: insert a needle in patient to obtain bone and bone marrow to look at closer X-rays, MRIs, and CT scans in order to view bone and organs for abnormalities such as tumors Treatment Options: Usually most patients are treated with a combination of both chemotherapy and radiation therapy. Often, stem cell or bone marrow transplants are used after these treatments. Target Therapy is often used, where drugs are used that targets specific cells. Along with these treatments, other various ones are used to fit the patients needs. Side Effects of Chemotherapy: Fatigue Nausea & Vomiting Pain Hair Loss Anemia Infection Blood Clotting Problems Mouth, Gum and Throat Problems Diarrhea and Constipation Nerve and Muscle Effects Effects on Skin and Nails Radiation Recall Kidney and Bladder Effects Flu-Like Symptoms Fluid Retention Effects on Sexual Organs and Sexuality Stages: There are no exact stages in Leukemia because it depends on different types of information regarding the patient. There are some basic stages made for certain types of leukemia, but they do not always apply. Those include 4 or 5 stages, each one where more and more WBC are replicating and more symptoms appear. Prognosis/Life Expectancy: AML - if detected early, only about 20- 40 % will make it past 5 years CLL - if detected early, about 10 - 20 years expectancy. However, can sometimes have a very low life expectancy if certain cells are affected ALL - 80 % chance of being completely cured in children, 40 % in adults CML - early stages: 8 years more, middle stages: 5-6, final stages: 3-4 Risk Factors: Genetic Mutations possibly exposure to smoke, benzene, and ionizing radiation sometimes an outcome from chemo or radiation therapy of a primary cancer New treatments and Clinical Trials: A new study involving turning patients blood cells into killers that "hunt and destroy" their own cancer cells. This has been successful with 3 patients with CLL, curing two, and improving another. Side effect: depletes antibody producing cells the end Rates (In 2009) Incidence Rate: 44,790 Mortality Rate: 21,870


Transcript: LEUKEMIA What is Leukemia? Many patients also experience no symptoms at all throughout early stages of the disease. -family history -Human T-cell leukemia virus type I (HTLV-I) -people with blood disorders Brainstorm National Cancer Institute Phone: 800-4-CANCER TTY: 800-332-8615 (cc) photo by Metro Centric on Flickr Symptoms: bone marrow failure paleness tiredness shortness of breath excessive bleeding increased susceptibility to infections THERE IS NO KNOWN CAUSE OF LEUKEMIA, BUT SCIENTIST CONTINUE THEIR RESEARCH! chemotherapy, targeted therapy, biological therapy, radiation therapy, and stem cell transplant. If the spleen is inlarged, it may be removed. Treatments scientist still do not know why some get leukemia and others do not. But some people who are more likely to get it are... Lots of treatments are done and stay active until the patient is in remission Who is prone to leukeimia? The rate of survival within the first five years is between 35 and 45 percent. The long-term survival rate for ALL is at 40 percent. Aside from complications caused by the leukemia itself, several of the treatments for leukemia may cause more complications. (cc) photo by jimmyharris on Flickr (cc) photo by Franco Folini on Flickr By: SavannahCagle and Kaleigh Leavell Illinois Department of Public Health Comprehensive Cancer Control Program 535 W. Jefferson St., Second Floor Springfield, IL 62761 Phone: 217-782-3300 TTY 800-547-0466 Leukemia and Lymphoma Society Phone: 800-955-4572 How do you get Leukemia? WHAT IS THE CAUSE OF LEUKEMIA? Leukimia is the accumulation of cancer cells in the bone marrow and blood. Presence of large numbers of abnormal cells in the bone marrow can cause the marrow from producing normal and healthy blood cells. Cancer cells can also infiltrate organs like the lymph nodes, spleen, and liver leading to swelling. American Cancer Society Phone: 800-ACS-2345 TTY: 866-228-4327 Complications of leukemia... get infections more easy bad immune system some patients blood clogs arterys some patients have excess bleeding very weak bones injured more easily can develop other types of cancer death Leukemia (cc) photo by Metro Centric on Flickr -people exposed to radiation -radiation thereapy -smoking -Chemotherapy -down syndrome Complications of Leukemia include a wide range of infections, blood problems and abnormal bodily functions. In some cases, complications may include developing another form of cancer and death. Even though death is possible with Leukemia, new research and better treatment options continue to improve the survival rate. The survival rate may depend on the type of leukemia. The Complications of Leukemia! Leukemia often affects the white blood cells, which protect the body against infection. The disease begins when normal stem cells develope into white blood cells goes wrong, creating abnormal white blood cells. These white blood cells are immature that they can't fight viruses like they are supposed to. Then the abnormal white cells take over other types of blood cells, including red blood cells, which carry oxygen to the body tissues, and platelets, which dont allow the blood to clot. Leukemia then interferes with the blood's ability to clot and carry oxygen.Cells multiply out some treatments for leukemia are.. * SUPPORT GROUPS *


Transcript: Leukemia Drums Girls and Dangerous Pie By: Charity Davis Story Written By: Jordan Sonnenblick Incidence of Leukemia In the United States, about 2,000 children and 27,000 adults are diagnosed each year with leukemia. The most common types of leukemia in adults are AML and CLL. ALL is very rare in adults, and is the most common form of leukemia in children. The incidence of leukemia is more common in men and boys than girls and women, and also more likely to occur in white people than black. Although people of any age can get leukemia, it is most common in adults over 60 years of age. What are the Risk Factors for Leukemia? For most types of leukemia, the risk factors and possible causes are not known. Some possible risk factors for leukemia include: • Previous cancer treatment: Certain types of chemotherapy and radiation therapy for other cancers. • Exposure to high levels of radiation: Exposure to high-energy radiation (e.g., atomic bomb explosions) and intense exposure to low-energy radiation from electromagnetic fields (e.g., power lines). • Chemical exposure: Long-term exposure to certain pesticides or industrial chemicals, like benzene. • Genetic diseases: Certain genetic abnormalities, such as Down syndrome, may play a role in the development of leukemia. • Gender: Men are more likely to develop CML, CLL and AML than women. • Age: The risk of most leukemias, with the exception of ALL, typically increases with age. • Smoking: Smoking cigarettes increases the risk of developing AML. • Family history: Most leukemias have no family link. However, first degree relatives of CLL patients, or having an identical twin who has or had AML or ALL, may put you at an increased risk for developing the disease. General Leukemia Symptoms: •Fever, chills •Fatigue, weakness •Loss of appetite, weight loss •Night sweats •Bone / joint pain •Abdominal discomfort •Headaches •Shortness of breath •Frequent infections •Easy bruising or bleeding •Petechiae (small red spots under the skin) Classifications Type A- Acute leukemia- In acute leukemia, the abnormal blood cells are immature blood cells (blasts). They can't carry out their normal work, and they multiply rapidly, so the disease worsens quickly. Acute leukemia requires aggressive, timely treatment. Chronic leukemia.-This type of leukemia involves more mature blood cells. These blood cells replicate or accumulate more slowly and can function normally for a period of time. Some forms of chronic leukemia initially produce no symptoms and can go unnoticed or undiagnosed for years. Type B- Lymphocytic leukemia- This type of leukemia affects the lymphoid cells or lymphocytes, which form lymphoid or lymphatic tissue. Lymphatic tissue makes up your immune system. Myelogenous (MI-uh-loj-uh-nus) leukemia. This type of leukemia affects the myeloid cells. Myeloid cells give rise to red blood cells, white blood cells and platelet-producing cells. The major types of leukemia are: Acute lymphocytic leukemia (ALL), which is most common in children, Acute myelogenous leukemia (AML), which occurs in both children and adults, Chronic lymphocytic leukemia (CLL), the most commonly adults leukemia and very rare in children,and Chronic myelogenous leukemia (CML), which mainly affects adults. My topic relates to this novel because Jeffrey has acute leukemia. It also adds an extra understanding for what these terms mean and why they are urgently rushing procedures. This topic showed me that there are things that we pass by everyday and dont understand that it can really affect us. Sources: - - Leukemia Leukemia — Comprehensive overview covers symptoms, causes, risk factors, treatment of this blood-related cancer. Definition Leukemia is cancer of the body's blood-forming tissues, including the bone marrow and the lymphatic system. Many types of leukemia exist. Some forms of leukemia are most common in children. Other forms of leukemia occur mostly in adults. Leukemia usually starts in the white blood cells. Your white blood cells are potent infection fighters — they normally grow and divide in an orderly way, as your body needs them. But in people with leukemia, the bone marrow produces a large number of abnormal white blood cells, which don't function properly. Treatment for leukemia can be complex — depending on the type of leukemia and other factors. But there are strategies and resources that can help to make your treatment successful. Symptoms Click to enlarge Petechiae may look like a rash and usually appear in clusters. Here they appear on a leg (A) and on an abdomen (B). PetechiaeLeukemia symptoms vary, depending on the type of leukemia. Common leukemia signs and symptoms include: Fever or chills Persistent fatigue, weakness Frequent infections Losing weight without trying Swollen lymph nodes, enlarged liver or spleen Easy bleeding or bruising Tiny red spots in

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