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Transcript: Carcinogenicity A recent analysis of both U.S. Food and Drug Administration (FDA) data and clinical trial data shows that nonbenzodiazepine Z-drugs at prescribed doses cause an increased risk of developing cancer in humans. There have been 15 epidemiological studies which have shown that hypnotic drugs cause increased mortality, mainly due to increased cancer deaths. Complex sleep-related behaviors Z-drugs induces amnesia type memory impairments similar to triazolam(Halcion) and Rohypnol. Potential side effects are: sleep walking, sleep eating, Other behaviors include making phone calls, having sex, and getting into the car and driving while not fully awake. Most people do not remember these events later. Various types of Hypnotic Drugs Barbiturate (Schedule II) Pentobarbital (Nembutal) Secobarbital (Seconal) Benzodiazepines (Schedule IV) triazolam (Halcion) temazioam (Restoril) Nonbenzodiazepines (Schedule IV) Zolpidem (Ambien) Eszopiclone (Lunesta) Zaleplone (Sonata) Over the counter sleeping pills Antihistamines (Unisom) Melatonin Is Ambien creating a nation of zombies? Risks Z-Drugs Z drugs - Ambien was the first to reach the U.S. market, in 1992 - are less likely to cause dependency and side effects than the older generation of benzodiazepines such as Ativan and Dalmane. Both classes of drugs activate the neurotransmitter that induces sleep, the gamma-aminobutyric acid (GABA) receptor complex.But the benzodiazepines also relax muscles and reduce anxiety - effects that can be beneficial but have the potential to cause respiratory failure and other muscle-related problems. And they often left users feeling drowsy for hours after awakening.Z drugs are more targeted; designed to activate a specific part of the GABA complex, they get you to sleep with fewer concerns about dependency and side effects.The Food and Drug Administration has approved Ambien and Sonata for short-term treatment of insomnia, up to five weeks. Lunesta and Ambien CR are approved for long-term use, up to six months. None of the Z drugs have been studied or FDA-approved for use longer than six months. Sleeping Pills About 30% of American adults have insomnia symptoms each year Americans spent about $2 billion on prescription sleep drugs in 2010 60 million prescription was written For centuries alcohol and opium were the only drugs available that had sedative-hypnotic effects. The first substance introduced specifically as a sedative and as a hypnotic was a liquid solution of bromide salts, which came into use in the 1800s. Chloral hydrate, a derivative of ethyl alcohol, was introduced in 1869 as a synthetic sedative-hypnotic; it was used notoriously as “knock-out” drops. Paraldehyde was introduced into clinical medicine in the 1880s and was followed by the synthesis of barbital in 1903. Phenobarbital became available in 1912 and was followed, during the next 20 years, by a long series of other barbiturates. In the mid-20th century new types of sedative-hypnotic drugs were synthesized, chief among them the benzodiazepines (the so-called minor tranquilizers).In 1990s, scientists were successful in developing non-benzodiazepine drugs (Z drugs). They are safer than the older barbiturates especially in overdosage and they may, when compared to the benzodiazepines, have less of a tendency to induce physical dependence and addiction, although these issues can still become a problem. History Risks Tolerance, dependence, and withdrawal A review medical publication found long-term use of zolpidem is associated with drug tolerance, drug dependence, rebound insomnia and CNS-related adverse effects. Abrupt withdrawal may cause delirium, seizures, or other severe effects, especially if used for prolonged periods and at high dosages Overdose An overdose of zolpidem may cause excessive sedation, pin-point pupils, or depressed respiratory function, which may progress to coma, and possibly death. Recreational Use As is the case with many prescription sedative/hypnotic drugs, it is sometimes used by stimulant users to "come down" after the use of stimulants such as amphetamines, methamphetamine, cocaine, and MDMA Date-rape drug According to the U.S. Drug Enforcement Administration, zolpidem (Ambien, Stilnox) is quickly overtaking illegal sedatives as the most common date-rape drug. Perpetrators of sexual assault have used zolpidem on unsuspecting victims Commercial Name: Ambien, Lunesta, Sonata

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Transcript: Major Customers Empanelled Vendor Why Liaising? What is needed? Solution Projects / Long Term Contracts TET (Primary teacher recruitment) CCTV in Elections KKR in IPL Finals Jyoti Basu's funeral B. Ed. College Multiple instances of Air conditioners / Television / Fridge Coffee / Tea machines Mobile phones / Tablets Copiers / Fax machines Websites Now we are looking for quality vendors for big business and long term relationships. Feature Presentation BNI Dreamz 24 years in IT - since 1992 Over 20 years with Government - since 1996 Over 95% turnover from Government Demand came from them Now we actively do it Why people don't do it? Work done in IT Credentials - proof of experience Standards & Quality - ISO and others Industry certifications, affiliations, prominence in trade association or chamber of commerce Awards, Certificates Tendering PPP / BOOT / Maintenance Most profitable Sell once, earn for years Low competition, high margins Service or Goods/Service combination Various agencies Direct orders Referral orders Indirect orders DGS&D Advance payment !!! Goods only or with standard service Fisheries Land & Land Reforms Fire Services Civil Defense Kolkata Police SIDCL WBSEDCL KMDA Minorities Affairs Tea Board Port Trust All RTO's All District Magistrates Sarva Shiksha Abhiyan Maneesh Kasera Director Venus IT Solutions Pvt. Ltd. Four modes Good quality at reasonable price Deep pockets Scalability Authorizations Registrations and compliance Trade Licence, VAT, Service Tax, PAN, Prof. Tax PF, ESI MSME, SSI, Import Licence, other relevant Ideal for retail business regular requirements small ticket size Closed tenders Various agencies Work done in Liaising Home P & AR Transport Education Health & Family Welfare Social Welfare Tourism Disaster Management PWD Panchayat & RD Maneesh Kasera My Company Red Tape Payments Contacts Entry barriers Involvement Competition Burnt Fingers Why Government? Least profitable Sometimes unavoidable Work before Spec to skew Statewide Medical College & Hospital networking Schools >1100 Colleges ~35 Driving Licence & Vehicle Registration Certificate Raktim & Thalamon Chief Minister / Chief Secretary Election / Gangasagar / Muharram / Haj Statewide - RTO (Motor Vehicles) Disaster Management Fisheries ICTC Mass Education & Libraries many more Too many to list here And almost everyone else with office in WB !!! LIAISON Rate Contract Liaising BIG orders BIGGER margins BIGGEST satisfaction Social responsibility Doing business with the Government Identify / create opportunities Develop a sales pitch Contact the right people Avoid tendering or influence it Pre-order paperwork Pricing advice Tender formalities and follow ups Procuring orders Deliver goods and services Get certificate of work done Post sales paperwork Getting the payments Getting the deduction certificates Getting the securities released Sales Related Empanelment Certification Licences Registration Rate contracts Subsidies Waivers Misc


Transcript: Hypnotic And the God of Sleep (Hamilton) Hypnos was the Greek God of sleep. He was also a personification of sleep meaning he was a living being of sleep. He is also referred to as the son of night. (Theio). Hypnos also had a lot of power of mortals and even the God of the Gods, Zeus. For example Hera was so mad with hercules she wanted to torture him but Zeus couldn't know so she asked Hypnos to do the deed. But this left Zeus very angry with Hypnos and told him to never do it again. Hypnos didn't listen and the temptation was too great so, he did it again.(Greekmyths) It would make perfect sense that the word Hypnotic comes from the God Hypnos because hypnotic means "to put into a state of sleep" ( And the God Hypnos is the personification of sleep which means he puts people into a rest like state. Next, the root word "hypno" comes from the greek Hypnos (englishforstudents) which would also mean sleep. In other words the God Hypnos would essentially hypnotize people as he put them to sleep, this act is very similar to how hypnotic drugs such as Intermezzo work, they are used to help people suffering from insomnia sleep during the night (rxlist). And then there are also certain methods of hypnotism that work very similarly to Hypnos such as hypnosis which is a form of hypnotherapy designed to "help individuals suffering from chronic insomnia" (Altmedicine) this is what Hypnos would do, by helping people go to sleep when they can't, and the people who put others to sleep act like Hypnos while they go through the process of hypnotizing. By helping people who struggle with insomnia hypnotists and hypnotic drugs are follwing in the footsteps of the God of sleep himself, Hypnos. From Hynos: Sleep (etymonline) Hypnotic: Artificially induced sleep that that resembles a normal sleep Hypnotic was derived from the god Hypnos reffering to the fact that when Hypnotized a person is put into a sleep-like state (Wiki) The God Hypnos Hypnotic And The Greek God Hypnos, The God of Sleep Hypnotic How they're related


Transcript: As a younger sister of a college student, I always heard about the late night study session craving. One night while staying with my sister in Lubbock, Texas I began craving something sweet (like a cookie) but I was to tired to go out and get one... What we need to start Location plans Each location is also a walk in bakery. So if you were in the area already you can pick out which cookies would want and take them in the car with you. Then "Hypnotic Cookies" was born. Hypnotic What We Are Just about any cookie you can dream of! From the classic chocolate cookie to salted caramel cookies. Even gluten free cookies for those among us who can't have gluten. We also sell milk and ice cream if you want it with your cookies. Cookies Getting the word out "Hypnotic Cookies" started with a craving. On average it takes about $10,000 to start bakery. All we ask for is $35,000 and 10%. If you chose to finance Hypnotic cookies you will help many college students survive the late night cravings. We will advertise on college websites and posters set around the campus, also we will advertise on different social media accounts like Instagram, twitter, Yik-Yak, and Facebook. We plan on placing our shops near every major college campus. If our company grows large enough, we will do a horizontal move with another major bakery like Insomnia Cookies Company. Our Sweet Story "Hypnotic Cookies" is a partnership company that provides a 24 hour cookie delivery service that delivers hot and fresh cookies straight to your door. What will we sell? We decided to be a partnership because I knew running a business by myself would be extremely difficult so I decided to ask my partner Savanna to help this business grow. In order to give back to our surrounding community we will give 15% of the proceeds to non-profit organizations that helps struggling college students who are trying to get an education. We even take new ideas from the community and if they get popular enough, we will keep them as a regular option.


Transcript: PICTURES!!!! Ambien, Ambien CR (zolpidem tartrate) Butisol sodium Carbrital (pentobarbital and carbromal) Dalmane (flurazepam hydrochloride) Doral (quazepam) Edluar Halcion (triazolam) Intermezzo (zolpidem) Methaqualone Chloral Hydrate Placidyl (ethchlorvynol) Prosom (estazolam) Restoril (temazepam) Rozerem (ramelteon) Seconal (secobarbital sodium) Sonata (zaleplon) Zolpimist WARNINGS For women, the standard recommended dosage of Ambien is 5 mg at bedtime. For men, the recommended dosage is 5 to 10 mg at bedtime. For people who are taking other medicines that affect the brain, have liver disease, or are older, the recommended starting dose may be Ambien 5 mg.Your Ambien dosage should be taken without food. Ambien is used for only one to two days. Ambien may not be safe during pregnancy. DOSAGE AND ADMINISTRATION AMBIEN COMES IN THE FORM OF TABLETS!!!!! ACTION AND USES SOURCE PAGE COMMON DRUGS These drugs can induce or tend to induce sleep. May impair mental/physical abilities.Worsening of depression and suicidal thoughts and actions.Caution with compromised respiratory function.Drowsiness, dizziness, headache, diarrhea, drugged feeling, lethargy, dry mouth, back pain, pharyngitis, sinusitis, allergy. Hypnotic drugs is an agent or drug that produces sleep; sedative. Ambien comes in tablet form and is taken once a day, immediately before bedtime. It is recommended that you take your dose with a glass of water, not after a meal, and not with food. HOW TO USE CLASSIFICATION HOW IS IT SUPPLIED * * * *http:/ * Ambien is only approved to treat insomnia in adults, age 18 years old and older. Specifically, it can help people who have difficulty falling asleep, who are waking up often during the night, or who are waking up too early in the morning. COMPOSITION Ambien is a sedative. It affects chemicals in your brain that may become unbalanced and cause sleep problems. Ambien is used to treat insomnia. Ambien can be ditributed in 5 or 10mg. HYPNOTIC BY: MIRANDA KING

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