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How are new medicines developed?

An overview of the development process for medicines
by

Paul Hill

on 9 June 2010

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Transcript of How are new medicines developed?

Drugs Medicines Narcotics substances intended for use in the medical diagnosis, cure, treatment, or prevention of disease substances that alters normal bodily function any psychoactive compound with morphine-like effects Pharmacology Pharmacy The study of drugs and their actions The science of making and dispensing medicines Today’s medicines are designed
to have specific effects – this is
becoming easier as we learn
more about the body’s
chemistry and begin to
understand the intricate
detail of the complex
molecules from which
we are made. 3000+ patients
Double-blind (against a PLACEBO)
Test therapeutic effects (statistics)
Identify potential harmful effects
Ethical implications (more effective or Placebo)
2-3 molecules 200-400 ‘paid’ patients
Different dose levels tested
8-15 molecule 50-100 volunteers
Given lowest possible doses
Test for toxicity
8-15 molecules
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