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How Do Muscles Work?
Transcript of How Do Muscles Work?
Andrew F. Huxley
A sarcomere extends from Z line to Z line. They each have thick filaments (Myosin) and thin filaments (Actin).
Leonardo da Vinci
What is the approximate number of skeletal muscles in the human body?
There are approximately 650 skeletal muscles in the human body.
How are skeletal muscles named?
Points of attachment
Number of muscle heads
Direction of muscle fibers
Major body actions
What is the structure of a sarcomere?
connects at the sternum, mastiod process and the clavicle
How would you describe the sliding filament model of muscle movement?
The thin filaments slide inward along the myosin filaments and the sarcomere is shortened. Its more of a gliding motion.
What is the power source for this movement?
How is this energy translated into the movement of the sarcomere?
How does this movement translate into movement of an arm or leg?
Comes from the latin word "chewer"
Muscle resembles a triangle
What is the structure of skeletal muscle?
consists of skeletal muscle tissue, connective tissue, nerve tissue, and blood or vascular tissue
can vary in size, shape, and arrangement of fibers
rect - meaning straight
located in front of the tibia
Lambert-Eaton myasthenic syndrome
What are the symptoms of this disease?
weakness of the bulbar muscles
weakness of the eye muscles
drooping of the eyelids
in advanced stages, weakness of the respiratory muscles
problems with coordination
disruption of the automatic nervous system, leading to dry mouth, constipation, impaired sweating, and orthostatic hypotension
Is the cause known? If so, describe the muscle defect?
LEMS is often associated with lung cancer (50-70%)
people with small cell lung cancer, 1-3% have LEMS
In some cases, LEMS is the first stage of lung cancer
also associated with autoimmune diseases, like hypothyroidism and diabetes mellitus type 1
What is the prognosis of the disease? Is it curable with the medicine of today?
the prognosis for this disease is often difficult to assess
treatment usually consists of chemotherapy since it is caused by lung cancer
By: Marissa Raygoza and Andrea Bran
A portion is released in this reaction then the process of binding action takes place and releases ATP
Muscles work in pairs to function. When one flexes the other relaxes. (Antagonism)