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BLAST: Keratin

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by

Sweta Patel

on 28 October 2012

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Transcript of BLAST: Keratin

BLAST Bioinformatics Directs the production of protein Keratin 1 Keratin 1 KRT1 Gene Keratin 1 Function: Continued Keratin 1 Predictions/Expectations Keratin 1 Is it possible to find the same gene in two different kinds of organisms but not find the protein that is produced from that gene? KRT 1 What if it's found in all tested organisms? Cladogram Horse KRT1 Other characteristics are still important in studies. Located on chromosome 12 Form keratinocyte cells Makes: skin
hair
nails Produced in epidermis Function Forms keratin intermediate filaments Assemble into strong networks Provide strength and resilience to skin Protect skin from damage due to: friction
physical stresses Found in skin on palms and soles of feet Protein is likely to be found in other organisms Primates
mice/rats
mammals in general Yes, it is possible. Several variations of skin skin on humans
scales on reptiles Organisms have a common ancestor Gene existed earlier in evolutionary tree Guinea pig African bush elephant Wild boar European rabbit Dog Rodents Primates Humans Keratin 1 similarities shows only part of relationship
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