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DNA Detectives

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by

Pedro Sanchez

on 13 January 2015

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Transcript of DNA Detectives

Strawberry DNA
SCIENCE
MEDICINE
What is a
Geneticist?
Dish Soap
Small Beaker or cup
Zipper Lock Bag
Strainer
Stick
Strawberries
1 salt pack
Salt
Isopropyl
Alcohol
Water
KEYS FOR A CAREER in
MEDICAL GENETICS
3C's & 2P's

Caring
Comprehensive
Competitive

Patient
Passionate
Explanation
Did you know that DNA is in
the food you eat? DNA is present in
every cell of all plants and animals and
determines the genetics of the individual
organisms
Strawberries are the perfect choice for a DNA extraction lab, because they yield more DNA than any other fruits, and they are octoploid, meaning that they have eight copies of each type of DNA chromosome. These special characteristics make strawberry DNA easy to extract and see.

To extract the DNA, each component plays a part. The soap helps to dissolve the cell membranes. The salt is added to break up protein chains that hold nucleic acids together, releasing the DNA strands. Finally, DNA does not dissolve in isopropyl alcohol. and even less so when
the alcohol is ice cold
Real life applications

- genetic engineering
- forensic science
- medicine
Thank You
Ms. Haydt
GUSD Students
Volunteers
Ms. Ibarra
Dr. Li
Principal Witt
Mrs. Bodnar
Mrs. Kim
Mrs. Nasif

Mountain Avenue
Science CLUB

DNA DETECTIVES
DNA DETECTIVES
Find your passion!!
Dr. Pedro. Sanchez, MD, MSCE, FAAP, FACMG

Dr. Laura Li, PhD, FACMG
UCLA 4 years
Undergraduate College
Major: Cell & Molecular
Biology
4 years Medical School
LEARNING
3 years Pediatrics
3 years Genetics
Enjoyed helping
KIDS
Families
Mystery Cases
PHILADELPHIA
Where can I find the instructions to make a person?
Why are my eyes brown?
Dr. DNA
POP QUIZ
What carries the instructions or blue print to make a person?
DNA
What is 3,000,000,000
letters long using only a
4 letter alphabet A C T G?
What substance is found in the nucleus of plant and animal cells?
DNA
What substance can be found at a crime scene that would identify the culprit?

What can be used to identify a specific killer shark?
DNA
What can a doctor test to see if a medical problem is genetic?
DNA
If we ever caught an alien:
What would we test to prove that they are not from this planet?
Why are my eyes Brown?
It's Genetic
Why do some dog breeds have more problems than others?
It's Genetic!
1965 Shelby Cobra Mustang
$1,000,000
UNIVERSITY PROFESSOR
Pediatrician & Geneticist
Children's Hospital
Los Angeles
What do these kids all have?
What Do These Kids Need?
Worried Parents
Caring
Parents
Down Syndrome
or
Trisomy 21
To have fun
Thorough physical examination
A doctor that knows about their genetic condition
WHAT IS DNA?
Pediatrician
Geneticist
Researcher
Medical Geneticist
4 years Undergraduate
5 1/2 year Ph.D. Training
4 years Post Graduate Fellowship
2 years Medical Genetics Training
46 Chromosomes

20,000 Genes

3,000,000,000 Bases

$1,000
Mr. van Breman
Coding & Programming
Pictures from flicker, google or or Presi
DNA
DNA
DNA
DNA
DNA
DNA
WHAT IS DNA?
Why do we have mutations?
ACTIVITY
Get in Groups of two
What is a "TRAIT"?
What features would you use to describe your partner?
10% of ALS is due to mutations in one of 8 genes
QUESTION: If there are 5000 new cases of ALS each year, how many will find a cause of their disease?
Clinical Genetic Molecular Biology Scientist Training
Takes time
Amyotrophic Lateral Sclerosis (ALS)
CODING
Why do people need a diagnosis?
To give them answers
To help them find others
To help them live healthier
1 year
Who has DNA?
Who will go
College?
What do you
love to study?
Dr. DNA
Full transcript