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Transcript of Methylprednisolone
History & Development
Discovered by Lewis Hastings Sarett of Merck Co. in 1944
Purposes of Methylprednisolone
Main Purpose :
To lessen inflammation in different areas of the body
Preparation of Methylprednisolone
Synthesized cortisone using a complicated 36 - step process to produce 18 mg
" All Available Biographical Memoirs. N.p., n.d. Web. 31 Dec. 2013. <http://www.nap.edu/readingroom.php?book=biomems>.
"Corticoids." Wikipedia. Wikimedia Foundation, 21 Dec. 2013. Web. 31 Dec. 2013. <http://en.wikipedia.org/wiki/Corticoids>.
"Invent Now | Hall of Fame | Search | Inventor Profile." Invent Now | Hall of Fame | Search | Inventor Profile. N.p., n.d. Web. 31 Dec. 2013. <http://www.invent.org/hall_of_fame/126.html>.
"Methylprednisolone." Wikipedia. Wikimedia Foundation, 21 Dec. 2013. Web. 31 Dec. 2013. <http://en.wikipedia.org/wiki/Methylprednisolone>.
National Center for Biotechnology Information. U.S. National Library of Medicine, n.d. Web. 31 Dec. 2013. <http://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0001175/>.
"Solu Medrol (Methylprednisolone Sodium Succinate) Drug Information: Side Effects and Drug Interactions - Prescribing Information at RxList." RxList. N.p., n.d. Web. 31 Dec. 2013. <http://www.rxlist.com/solu-medrol-drug/side-effects-interactions.htm>.
By: Ryanne Harris
Brand Names: Medrol, Solu-Medrol, Depo-Medrol, Hybrisil, A-Methapred
Chemical Formula: C22H30O5
- Merck Co. is an American pharmaceutical company who was trying to improve military medicine
1948, Mayo Clinic demonstrated it as an effective treatment for rheumatoid arthritis
What is Methylpredisolone? - A steroid drug
Used to treat different medical conditions such as:
-bone marrow problems
It does NOT replace anything ( medical conditions) because it only treat them
The benefits are a relief of severe, painful medical conditions
Fun Facts About
Consumed in 2 ways:
-by mouth (pills)
-loss of muscle mass
- mood swings
-decreased resistance to infections
- impaired wound healing
January 15, 2014