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Ryanne Harris

on 14 January 2014

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Transcript of Methylprednisolone


Basic Information
Methylprednisolone (Meth-ill-pred-nis-alone)
History & Development
of Methylprednisolone
Discovered by Lewis Hastings Sarett of Merck Co. in 1944
Purposes of Methylprednisolone

Main Purpose :
To lessen inflammation in different areas of the body
Preparation of Methylprednisolone
Synthesized cortisone using a complicated 36 - step process to produce 18 mg
Works Cited

" All Available Biographical Memoirs. N.p., n.d. Web. 31 Dec. 2013. <http://www.nap.edu/readingroom.php?book=biomems>.

"Corticoids." Wikipedia. Wikimedia Foundation, 21 Dec. 2013. Web. 31 Dec. 2013. <http://en.wikipedia.org/wiki/Corticoids>.

"Invent Now | Hall of Fame | Search | Inventor Profile." Invent Now | Hall of Fame | Search | Inventor Profile. N.p., n.d. Web. 31 Dec. 2013. <http://www.invent.org/hall_of_fame/126.html>.

"Methylprednisolone." Wikipedia. Wikimedia Foundation, 21 Dec. 2013. Web. 31 Dec. 2013. <http://en.wikipedia.org/wiki/Methylprednisolone>.

National Center for Biotechnology Information. U.S. National Library of Medicine, n.d. Web. 31 Dec. 2013. <http://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0001175/>.

"Solu Medrol (Methylprednisolone Sodium Succinate) Drug Information: Side Effects and Drug Interactions - Prescribing Information at RxList." RxList. N.p., n.d. Web. 31 Dec. 2013. <http://www.rxlist.com/solu-medrol-drug/side-effects-interactions.htm>.
By: Ryanne Harris
Honors Chemistry
Brand Names: Medrol, Solu-Medrol, Depo-Medrol, Hybrisil, A-Methapred
Chemical Formula: C22H30O5
- Merck Co. is an American pharmaceutical company who was trying to improve military medicine
1948, Mayo Clinic demonstrated it as an effective treatment for rheumatoid arthritis
What is Methylpredisolone? - A steroid drug
Used to treat different medical conditions such as:
-severe allergies
-bone marrow problems
-vision problems
-kidney problems
-skin problems

It does NOT replace anything ( medical conditions) because it only treat them
The benefits are a relief of severe, painful medical conditions
Fun Facts About

Consumed in 2 ways:
-by mouth (pills)
Side effects:
- acne
-loss of muscle mass
- mood swings
-decreased resistance to infections
-weight gain
- impaired wound healing
January 15, 2014
Full transcript