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3/14 Blood Types & Switched at Birth

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Mr. Bowen

on 15 March 2018

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Transcript of 3/14 Blood Types & Switched at Birth

1) What is the Human Genome Project?
2) What is the relationship between a gene and a protein?
3) What’s the function of a punnett square?
4) Why is knowing someone's blood type important?

Announcements
Switched at Birth?

- Genetics Exam on Friday 3/16

- Final Draft Due Friday 3/16

- Office Hours after school & at break

How could you tell if someone were switched at birth?
Sequencing a Human Genome:
Then
Now
$2.7 Billion
<$1,000
13 years
20 Minutes
Parental DNA Testing:
Still costs around $200 per family.
Blood Type NOTES 3/16
When life first went from single cells to many cells they needed to tell the difference between their cells and cells of other organisms.
So cells have special Identifier Proteins. They are called Antigens.
If an invader cell is found the immune system will destroy it.
One way the immune system destroys invaders is by making Antibodies.
Antibodies are special proteins that attach to the invader’s Antigens.
Because humans are so closely related to each other it’s common for us to share Antigens (ID Proteins).

Then, they found that sometimes when you gave blood to someone their body rejected it and they died.
Blood Type:
In one location on chromosome 9 there is a gene that codes for the Blood Type Antigens.
There are 3 allele types: A, B, and O.
- A & B are codominant. O is recessive.
- What are all the possible genotypes?
Type A = AA or AO = kill Type B antigens
Type B = BB or BO = kill Type A antigens
Type O = OO = kill both Type A & B antigens
Type AB = AB = kill no other antigens
Carefully read and interact with the story. Then solve the problem using what you know about blood types. You will have to use several punnett squares.

When you've solved the problem, write a full letter to the hospital explaining your proof.
white blood cell
white blood cell
Does everyone belong?
Type A = AA or AO
Type B = BB or BO
Type O = OO
Type AB = AB
Cross Type-A with Type-AB:
Cross Type-A with Type-AB:
AA/AO
AB
A
A
A
A
A
O
B
B
Cross Type-A with Type-AB:
AA/AO
AB
A
A
A
A
A
O
B
B
AA
AA
AA
AB
AB
AB
AO
BO
"That's my kind of...Blood Type!"
genotype
phenotype
Finish up your "Human Genome Project" Assignment
Biofresh 3/14 π
1) How much did the
Human Genome Project cost?
2) What’s the function of a
punnett square?
3) Why is knowing someone's blood type important?
4) What are the different blood types?
5) What is the relationship between genotype and phenotype?
6) Have you ever watched "Switched at Birth"?
R.I.P.
In the 1600s doctors discovered blood transfusions, when you give someone extra blood to save their life.
Why do we need TWO punnett squares to cross AB with A?
Full transcript