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Genetics after Mendel

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by

Linda Arfin

on 14 October 2015

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Transcript of Genetics after Mendel

Codominance
Occurs when two alleles are
equally

dominant
The heterozygous condition results in
both
phenotypes being equally expressed.
Incomplete dominance
Occurs when one allele
influences
the second allele.
The heterozygous condition produces an intermediate phenotype
Genetics after Mendel
Multiple Allelism
More than two different alleles exist for a particular gene
Results in a larger number of possible
genotypic
combinations and a greater variety of
phenotypes
Linkage
Sex-linkage
Human
X chromosome
is large and contains many genes while the
Y chromosome
contains only a few.
Complex patterns of inheritance
Genetics after Mendel
Example: Red-green colourblindness
Alleles of different genes found on the same chromosome
Let's take a closer look...
Example: Red and white horses / cows
List the genotype and phenotype probabilities of the offspring resulting from a white horse crossed with a red horse.
Example: White and red snapdragons
List the genotype and phenotype ratios for the offspring between a red snapdragon crossed with a white snapdragon.
Example: Human blood types (A, B, O)
100% Roan horses
Example
Linked genes do not separate from each other unless
crossing over
occurs.
1 normal female: 1
carrier
female : 1 normal male: 1
colour-blind
male
Phenotype Ratio:
3rd phenotype
=
= diversity
=

linked genes
Do not assort independently
So only 1 allele for the disorder results in the male being affected
Notice there are no alleles on the Y chromosome
Example: Hemophilia
Phenotype Ratio:
1
carrier
female: 1
hemophiliac
female: 1 normal male: 1
hemophiliac
male
Let's take a look at the way we write the alleles...
A woman with Type O blood claims a man with Type AB blood is the father of her Type O blood son. Is this possible? Explain your reasoning using a Punnett square.
Example: Red-green colourblindness
Colourblindness is a
recessive X-linked
disorder.
What are the allele combinations present in the gametes?
Full transcript