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Bioinformatics

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by

bilal syed

on 13 January 2014

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Transcript of Bioinformatics

Potential
Uses
Current Research Project
Current Uses
Pros
screening of fetus/newborns
detecting diseases
promotion of gene therapies
businesses can screen applicants
we know our own genetic make-up
Cons
Bioinformatics
Gene Therapies
method to cure or prevent disease
eradicating a disease by altering the genes in an organism
Personalized Medicine
use of info gathered from pharmacogenetics
many drugs fail to make it to the market
Definition
managing biological information via application of computer technology
Genomics
sequencing and analysis of genomes in an organism
By: Bilal Syed
Agenda
Definition

Current Uses

Potential Uses
Current Research Project

Pros & Cons
gather, store, and analyze biological and genetic information
can be applied to discovery and development of gene-based drugs
Proteomics
analysis of entire proteome in an organism
Metabolomics
study of metabolites in organisms
Pharmacogenetics
study of effects of medicine and treatments on different people
Transcriptomics
analysis of transcriptome in an organism
The Human Metabolome Project
launched by Genome Canada
started in January 2005
$7.5 million project
genetic make-up of organisms
genes(DNA): functional and physical unit of heredity
proteins that are produced according to genes
DNA
RNA
PROTEINS
Transcription
Translation
transcripts(RNA): copy of section of DNA
variation is caused by differences in genetic make-up
used to optimize the positive effects of the medicine or treatment on patients
metabolites: small molecules needed for metabolism
metabolism: all of the chemical processes that take place in an organism to maintain life
cancer, Hemophilia, etc.
a small group of people show adverse effects to the drug
Objectives:
research metabolomics to:
improve disease identification
link human metabolome and genome
develop software tools for metabolomics
should bioinformatics be included on medical records?
who is able to access these records?
insurance companies
invasion of privacy
should you be assessed on your genes or your skills, experience, etc?
Full transcript