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Short presentation of ongoing work Unit of Survivorship
Christoffer Johansenon 2 December 2015
Transcript of Short presentation of ongoing work Unit of Survivorship
'Translational research - from problem identification to bedside intervention'
RCT Intervention projects
REBECCA (patient navigator)
PROCAN (sexual counseling prostate couples)
WEBCAN (guided follow-up)
PACO (social support lung cancer)
TJEK (prevention social disadvantaged)
DOMUS (care and death at home)
FAMOS (support childhood cancer families)
Three senior researchers within three disciplines of survivorship cancer research
Somatic disease following treatment in clinical data bases and registries: lymphoma, breast cancer, testicular, head & neck, childhood
Late effects in lymphoma survivors, in testicular cancer survivors and in head & neck cancer survivors
Social inequality (Susanne Dalton), Psychology (Pernille Bidstrup) and Childhood cancer (Jeanette Falck Winther)
Professorship at Rigshospitalet in Cancer late effects
Breast cancer and use of antidepressant medication, polymorphisms and depression
Social factors and survival from gynecologic cancers
December 2013: 15 phd students - in house or at other universities
Dreams - applications
MyHealth - follow-up program
Social disadvantaged in trials
Social 'inequality laboratorium'
Late effect cohort - in the clinic at Rigshospitalet
More biochemistry, e.g., genetic risk factors for neuropathy and clinical exam as part of studies
Combine clinical, administrative and subjective data in studies -
achieve the highest quality.
Always need for implementing genetic factors but expensive and underdeveloped
What is the effect of a cancer disease and the treatment - integrating comorbidity, psychological and social factors
Is it possible to address these effects in the clinic
The problem with 'phd factory' and lack of experienced researchers
Lack of core positions
Lack of time, staff and funding for development of ideas
Mobile phones; electromagnetic fields, glioma genes,
Major findings in the risk for depression in adults (Dalton, JCO, 2009 & Mitchell, Lancet Oncology 2011) and children (Lund, Lancet Oncology 2013)
Behavioral research has lacked manuals of interventions - we work on this important aspect
Identify problems in the life of cancer survivors
Collaborate with clinicians
Implement observational findings in RCT's to detect effect of manual-based and theory driven interventions
By relatively simple instruments we are able to create scientific evidence of the effects of cancer treatment
The most difficult part is to predict who will be diagnosed with these effects, prevent and detect them early in the trajectory of cancer treatment
The focus for our translational activities during the next years