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Morphine
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kristen battista
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Updated Dec 14, 2020
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00:01 - 00:04
Oh, sorry, Didn't see you there.
00:04 - 00:07
Um, yeah, it's been really tired lately.
00:07 - 00:09
My doctor gave me this medication because I had this
00:10 - 00:13
foot surgery the other day, and I was, I've been
00:13 - 00:13
a lot of pain.
00:14 - 00:17
Just make me really nauseous, Really tired all the time.
00:17 - 00:18
My heart's been racing.
00:18 - 00:21
It's been really itchy, I don't know, but it's called
00:22 - 00:25
morphine. So I tried Thio do some research on to
00:25 - 00:27
see, like what it actually is.
00:29 - 00:31
So it's this chemical compound that's made up of a
00:31 - 00:36
benzene ring and some alcohol groups with the chemical formula
00:37 - 00:39
of C 17, 18, 19 and a three.
00:40 - 00:44
It's a natural substance, and it's an opioid found within
00:44 - 00:45
the natural plant PayPal.
00:46 - 00:51
So it's a plant alkaloid, and it is found in
00:51 - 00:53
18 06 by the chemist Suttner.
00:54 - 01:00
It's not very soluble in water, and it is also
01:00 - 01:04
known as God's drug M s or dreamer On street.
01:06 - 01:10
It's a big molecule, and it weighs 285.34 grand from
01:10 - 01:12
all the Ph is 8.5.
01:13 - 01:13
It's a basic molecule.
01:14 - 01:16
If you look at the structure, you could see it
01:16 - 01:20
has five stereo centers with five Cairo centers at 569
01:22 - 01:23
13 and 14 carbons.
01:24 - 01:27
It's a five bring molecule has a tertiary carbon linked
01:27 - 01:30
to tertiary amine group, with two nearby and carbon atoms.
01:31 - 01:34
It's able to donate to hydrogen and, except for hydrogen,
01:34 - 01:36
is and it's an odorless and solid compound.
01:37 - 01:41
Morphine can either be swallowed orally or injected via I
01:41 - 01:44
V and enters the blood stream and goes deliver to
01:44 - 01:47
be detoxified, in which about 50% will go to the
01:47 - 01:49
central nervous system, which is the brain and the spinal
01:49 - 01:53
cord, in which in the brain it will bind to
01:53 - 01:58
the opioid receptors and will impact the central nervous system.
01:59 - 02:02
Then the receptors released this feeling of euphoria, which will
02:03 - 02:06
give you this feeling that your pain has decreased, and
02:07 - 02:09
it could also impact other systems in your body, such
02:09 - 02:12
as the respiratory and digestive systems, which can actually have
02:13 - 02:13
adverse effects.
02:14 - 02:17
It also has a half life of 120 minutes, so
02:17 - 02:19
that's about two hours to take.
02:19 - 02:22
For the drug to be reduced in half due to
02:22 - 02:25
its lipid soluble ITI, which is poor, it's able to
02:25 - 02:27
pass the blood brain barrier in the brain.
02:28 - 02:31
That's how it's able to attach to these receptors with
02:32 - 02:33
the main goal being pain relief.
02:33 - 02:35
There's obviously still some adverse effects.
02:35 - 02:37
Like I said, if the doctor prescribed this to me,
02:37 - 02:42
I could still experience this constipation, tiredness, respiratory depression, which
02:42 - 02:43
could be very serious.
02:43 - 02:45
The normal is 12 to 20 breaths per minute, but
02:46 - 02:48
if it goes below eight, you could go into respiratory
02:49 - 02:52
failure. Which, as you know, if you don't breathe, you
02:52 - 02:52
can't do bodily functions.
02:53 - 02:55
Etcetera. Also, nausea, confusion.
02:55 - 02:58
All these could be very seriously in a quick amount
02:58 - 02:58
of time.
03:00 - 03:03
It is very dangerous morphine due to its effects, to
03:03 - 03:06
be able to be an addictive substance very easily.
03:07 - 03:11
A tolerance has been noted to be developed very quickly
03:11 - 03:11
with morphine.
03:12 - 03:14
So if I were to be on 5 mg of
03:14 - 03:18
morphine, I would need 6 mg or 8 mg to
03:18 - 03:22
get the same effects as I originally Onley five in
03:23 - 03:26
the beginning, because I developed ah tolerance to the drug
03:26 - 03:29
and then eventually I will become dependent on it and
03:29 - 03:33
then once it's occurs and once I developed this bodily
03:34 - 03:37
and psychological need for it, I will become addicted to
03:38 - 03:41
the drug, which is very serious conviction is never planned
03:42 - 03:46
as it is caused by Sensation and many people who
03:47 - 03:47
are addicted to drugs.
03:48 - 03:50
It's when they desire and they can't control the feeling.
03:51 - 03:53
And these opioids, such as morphine, are prescribed by doctors,
03:54 - 03:57
and this is obviously not planned for their patients to
03:57 - 03:58
become addicted to opioids.
03:59 - 04:00
And there's opioid crisis globally.
04:01 - 04:05
And I think many medical professionals are reconsidering prescribing opioids
04:05 - 04:08
in controlled substances due to the effects they see with
04:08 - 04:12
addiction. Other mentions to note is that that is, It's
04:12 - 04:15
big Norman, please your name and its boiling point is
04:15 - 04:18
190 degrees, and its melting point is 255 degrees My
04:19 - 04:19
molecules up there.
04:20 - 04:21
But I also have it built here.
04:21 - 04:22
Here's from a couple of different angles.
04:24 - 04:27
It's important to note that the structure can also be
04:27 - 04:29
easily changed to make other molecules.
04:29 - 04:30
So if you take the O.
04:30 - 04:33
H group off right here and convert it to a
04:34 - 04:36
meth OCS group right there through methylation, you can convert
04:37 - 04:41
morphine to coating, which is another opioid, and it caused
04:41 - 04:42
a similar effects on the body.
04:43 - 04:46
But this is due to the change in structure as
04:46 - 04:49
structure as we all know determines function in conclusion.
04:49 - 04:52
Morphine is a very powerful drug and should be prescribed
04:53 - 04:56
with caution, as it has many serious effects.
04:57 - 05:00
But is an overall a very good prescription for pain
05:00 - 05:03
relief? Happy holidays, Dr MacDougal.
05:03 - 05:04
Merry Christmas.
05:04 - 05:06
And here is my We're excited.
05:06 - 05:10
Page. Have a good year.
05:10 - 05:10
Merry Christmas.
05:11 - 05:11
Happy holidays.
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