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síntesis del diclofenac sódico

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by

Ixchel Telleria

on 3 December 2014

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Transcript of síntesis del diclofenac sódico

síntesis del diclofenaco sódico
CLCH COCL
2
AC O
2
K CO ,Cu,
2
3
S A
NR r
NaOH
H O,
2
Et N, CH CL
3
2
2
2,6- dicloreacetanilida
ácido acético
2,6- dicloroanilina
2,6- dicloreacetanilida
NaOH
H O,
2
N-fenil-N-2,6-dicloroanilina
AlCl
160°C, 2 h
3
NaOH
H O
2
Química 5to año



Alumna: Ixchel Tellería
Diclofenaco Sódico
Mecanismo: sustitución en el carbono carbonílico
Mecanismo: sustitución nucleofílica aromática
Bencino
ácido carbónico
mecanismo: hidrólisis básica de amidas
Mecanismo: Hidrólisis
¿Qué es el diclofenaco sódico?
Es un medicamento antinflamatorio no esteroide (AINE).

Gracias por su atención
o
l
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