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ESOXX One - Reason to believe One

Product Profile of ESOXX ONE, the only treatment able to target the esophagus, the real symptoms' site of GERD
by

rodolfo perriccioli

on 27 June 2016

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Transcript of ESOXX One - Reason to believe One

Esoxx

Each Sachet a day...Keep GERD away!!!
GERD
Episodic (at least twice a week) onset of symptoms like heartburn, acid regurgitation, chronic cough and complications such as esophagitis and laryngitis.

Regardless of the patient’s age,
GastroEsophageal Reflux (GER)
is defined as the involuntary passage of gastric contents into the esophagus;
it is a normal, physiological process
, which occurs several times a day in everybody,
causing few or no symptoms
.

Erosive Reflux Disease
(ERD)
Is there only 1 GERD?
GERD
Multifactorial disease

in which many factors are involved:
- Altered gastric motility
- Mucosal Hypersensitivity
- Exposure to bile acids, pepsin, etc.
- Poor defense mechanisms
- Etc.
Innovation and Tecnology
for improvement in GERD
Conversely,
it may represent a
pathological condition (GERD),
when it causes symptoms or complications
that are associated with significant morbidity.

Typical symptoms
Atypical symptoms
...not just an acid related disease!
Non-Erosive
Reflux Disease
(NERD)
How can we manage patients with GERD?
Acid controlling therapies:
PPIs
H2-Antagonists
Antiacids
Other therapies:
- GABAb agonists
- Alginates
- ESOXX®
Prokinetics (cisapride, metoclopramide, domperidone) and antidepressants (tricyclics, SSRIs) are rarely prescribed.
All currently available treatments for GERD target the stomach, while all symptoms are generated by the esophagus.

ESOXX ONE is the only GERD treatment
that targets the esophagus,
the real symptoms site of GERD
1. DISEASE
2. ETHIOLOGY
3. PATIENTS
4. MANAGEMENT
5. ESOXX
The
only way
to
directly
act on the
symptom site
of GERD is using
ESOXX
Brand Promise
will
double the efficacy

of GERD treatment
,
when associated to PPIs, significantly improving
typical and atypical symptoms.

Brand Story
innovates
,
being the only treatment
able to improve GERD symptoms
directly targeting the esophagus
, the real symptoms site of GERD.
A
new technology

allows
ESOXX ONE
to create a
protective layer on the esophagus
and helps GERD patients in improving typical and atypical symptoms and in healing mucosa.
significantly increases the rate of patients with symptoms improvement.
Clinical Evidence
+64%
+49%
+54%
is targeted to GERD patients not controlled by PPIs
Patients' profile
Recommended dose is 1 to 2
sachets a day
After main meals
+
1 before bedtime
For 14 days
Severe
patients
1st step to:
- increase efficacy perception;
- create Advocates;
- open the road to other treatment schemes.
is not recommended for
on demand treatment
Recap:

1. GERD, by definition, is based on the onset of symptoms;

2. Symptoms are not only generated by acid reflux;

3. Many different GERD patients are there;

4. All available GERD treatment target the stomach.

Regurgitation
Heartburn
Etc.
Chest pain
Dysphagia
Extraesophageal symptoms
(like Cough, Laryngitis, Asthma
Sleep disturbancies, etc.)
Etc.
Delivery Date
ESOXX
Full transcript