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Chapter 2 Review of Concepts

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by

Jacqueline Semaan

on 25 August 2016

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Transcript of Chapter 2 Review of Concepts

1. Receptor Sites
Agonists
Competitive Agonists
Non-Competitive Agonists
2. Drug-Enzyme Interactions
3. Selective Toxicity
Pharmacodynamics
Chapter 2 Review of Concepts
Critical Concentration
Loading Dose
Dynamic Equilibrium
Pharmacokinetics
Routes of Administration (Table 2.1)
IV
IM
SQ
PO
PR
Sublingual, buccal
Topical
Inhalation
Passive Diffusion vs. Active Transport
Absorption
Factors:
Tissue Perfusion
Lipid Solubility
Ionization
Molecular Size
Protein Binding
Blood-Brain Barrier
Placenta - Breast Milk
Distribution
First Pass Effect
Hepatic Enzyme System
Enzyme Induction
Hepatic Disease
Metabolism
Kidney
Glomerular Filtration
Urine Acidity
Half-Life
Excretion
Weight
Age
Gender
Physiologic and Pathological Factors
Genetics
Immunological
Psychological
Environment
Factors Influencing Drug Effect
Tolerance
Cummulation
Interactions
Drug-Drug
Drug-Food
Drug-Natural
Drug-Laboratory Test
Factors Effecting Drug Effects
Full transcript