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Anatomy & Physiology: The Blood
Transcript of Anatomy & Physiology: The Blood
~45% RBCs (hematocrit)
>1% WBCs and platelets (buffy coat)
Red Blood Cells (Erythrocytes)
no nucleus (to make room for
the big molecule hemoglobin)
therefore, all die within 120 days
heme - iron component
globin - protein component
transports Carbon dioxide
How does the RBC transport blood gases?
Formation of RBCs
Regulated by erythropoietin (EPO)
- low oxygen carrying capacity
- not a disease, a symptom
White Blood Cells
Granulocytes - short life
basophils - blue
eosinophils - red
neutrophils - purple
Agranulocytes -long life
lymphocytes (T and B cells)
monocytes - macrophages
Never ~ 60%
Let ~ 20%
Minions ~ 8%
Eat ~ 2%
Bananas ~ <1%
Fragments of the megakaryocyte
formation of prothrombin activator
Thrombus v. Embolus
four main blood types
WHAT COLOR IS BLOOD???
How many RBCs are there?
there are about 5 million RBCs/cubic mm
1 cubic cm = 1000 cubic mm
1 cubic cm = 1 ml
1 ml of blood = 5 billion RBCs
1000 ml = 1L
5 L of blood/person
there are about
5 billion RBCs/ml x 5000 ml
which equals roughly
25 trillion RBCs/person
60, 20, 8, 2, 0
Never, Let, My, Engine, Blow
(clumping of cells)
You are working with the police investigating a murder. An unknown sample of blood was left at the crime scene. Upon testing, you discover that the blood reacted with Anti-A serum, but not Anti-B nor Anti-Rh. What was the blood type of the unknown sample?
an exception (but not human)
If there is 5-6 L of blood in the body...
Massive Pulmonary Embolism