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Lung Cancer

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Luke Kirmelewicz

on 8 January 2014

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Transcript of Lung Cancer

Causes: NSCLC
Some Causes of lung cancer are Cigarette, pipe, or cigar smoking. Exposure to second-hand smoke, radon, arsenic, asbestos, chromates, chloromethyl ethers, nickel, polycyclic aromatic hydrocarbons, radon progeny, other agents, and air pollution. Also Chest or Breast radiation exposure. If lung cancer runs in the family, chances are greater of haveing lung cancer.
Treatment: NSCLC
Occult NCSLC:
Stage 0 NSCLC:
Surgery and Endobronchial Therapies
Stages IA and IB NSCLC:
Surgery and Radiation Therapy
Stages IIA and IIB NSCLC:
Surgery, Neoadjuvant Chemotherapy, Adjuvant Chemotherapy, and Radiation Therapy
Surgery, Neoadjuvant Chemotherapy, Adjuvant Chemotherapy, Radiation Therapy, Chemoradiation Therapy, Radiation Therapy, Concurrent Chemotherapy
Sequential or Concurrent Chemotherapy and Radiation Therapy.
Cytotoxic Combination Chemotherapy, Combination Chemotherapy with Bevacizumab or cetuximab, EGFR Tyrosine Kinase Inhibitors, Maintenance therapy following first line therapy, Endobronchial laser therapy and/or Brachytherapy, and External-Beam Radiation Therapy
Recurrent NSCLC:
Radiation Therapy, Chemotherapy or kinase inhibitors, EGFR inhibitors in patients with/without EGFR mutations, EML4-ALK inhibitors in patients with EML-ALK Translocations, Surgical resection of isolated cerebral metastasis, Laser Therapy or interstitial radiation therapy, and Stereotactic radiation therapy
About 228,190 new cases of lung cancer (118,080 in men and 110,110 in women). An estimated 159,480 deaths from lung cancer (87,260 in men and 72,220 among women), accounting for about 27% of all cancer deaths. More than 380,000 people alive today have been diagnosed with lung cancer at some point. About 2 out of 3 people diagnosed with lung cancer are 65 or older. Black men are about 20% more likely to develop lung cancer than white men.
Lung Cancer
The most common symptoms at presentation are worsening cough, shortness of breath, and dyspnea. Other presenting symptoms include the following:
-Weight loss
-Chest pain

-Physical Examination
-Routine laboratory evaluations
-Chest x-ray
-Chest CT scan with infusion of contrast material(NSCLC)
-Chest computed tomography scan with infusion of contrast material(SCLC)
Limited-Stage disease:
Chemotherapy and Radiation Therapy, Combination Chemotherapy alone, surgery followed by Chemotherapy or Chemoradiotherapy, and prophylactic cranial irradiation
Extensive-stage disease:
Combination Chemotherapy, Radiation therapy, and prophylactic cranial irradiation
Recurrent disease:
Chemotherapy and Palliative Therapy
In normal cells, if they are damaged, they die and are replaced by new cells as needed. Sometimes, cells are made when not needed or dont die after being old or damaged and this causes a build up.The build up of cells is called a tumor. Tumors in the lung can be benign (not cancer) or malignant (cancer).
Cancers that begin in the lungs are divided into two major types,
Non-small cell lung cancer
small cell lung cancer
, depending on how the cells look under a microscope. Each type of lung cancer grows and spreads in different ways and is treated differently.
Non-small cell lung cancer(NSCLC)
NSCLC is any type of epithelial lung cancer other than small cell lung cancer(SCLC). NSCLC is not as easily cured with chemotherapy and radiation therapy compared to SCLC. Although NSCLC is connected with cigarette smoke, some patients with NSCLC have never smoked in their life.
Small Cell Lung Cancer(SCLC)
SCLC is more responsive to chemotherapy and radiation therapy than Non-Small Cell Lung Cancer. However, finding a cure is difficult because SCLC has a greater tendency to be widely disseminated by the time of diagnosis.
Essential Question
A cell that is becoming cancerous takes awhile to reach that point. A cell will change over time, a result of damage to between three and seven of the hundreds of genes that control cell growth, division and life span. First, the cell starts to grow and multiply. It is possible that the cell and its offspring could become immortal, avoid destruction by the body's defenses, develop their own blood supply and invade the rest of body.

I feel that to spread cancer awareness, teens should regularly post things about cancer on social networking sites.
Symptoms: NSCLC
The most common symptoms at presentation are worsening cough or chest pain. Other presenting symptoms include the following:
-Weight Loss
Symptoms: SCLC
-Radon: a radioactive gas made by the normal breakdown of uranium in soil and rocks.
-Air pollution
-Arsenic in drinking water
-Radiation treatment to lungs or breast area
If lung cancer runs in the family, chances are greater of having it.
Causes: SCLC
Don't start smoking or stop smoking, don't be exposed to radon, Asbestos, Air pollution, Arsenic in your drinking water, and Radiation treatment to lungs or breast area
My name is Luke Kirmelewicz. I chose Lung Cancer because it is the most common type of cancer and I wanted to learn more about it.
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