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Graves' Disease

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Toni Schmidt

on 28 March 2013

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Transcript of Graves' Disease

Toni Schmidt Graves' Disease Who? Symptoms Graves' disease most common is women over the age of twenty.
Graves' disease can occur at any age and may effect men as well.
About five out of ten thousand people have Graves' disease. Classification and Mechanisms Type III - Immune complex reaction
Type III pathogenesis occur in four steps:
1.Exposure to extreme amounts of antigen which causes
2.The body’s immune system to produce large amounts of antibodies.
3.When the antibodies and antigens interact with each other they produce free- floating compounds
4.that can accumulate in tissues causing a immune complex reactions or diseases. Anxiety
Bugling eyeballs
Fatigue
Insomnia
Weight loss
Increase appetite
Sweating more
Irregular or rapid heartbeat
Eye irritation Diagnosis Blood test are used to measure the amounts of thyroid stimulating hormone (TSH), Thyroxine (T4), and triiodothyronine (T3) Treatment Treatment for Graves' disease is not for the purpose of curing the disease, but to control the over active thyroid gland that is the cause of Graves'
The three main treatments are:
Antithyroid medicines
Surgey
Radioactive iodine Outcome If surgery or radiation is used in the treatment of Graves' disease, the thyroid would be either removed or destroyed due to the treatments, so you would have to take replacement thyroid hormones for the rest of your life. Resources PubMed Health
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001398/
Mayo Clinic
http://www.mayoclinic.org/graves-disease/diagnosis.html
Johns Hopkins Medical Institutions
http://autoimmune.pathology.jhmi.edu/diseases.cfm?systemID=3&diseaseID=21
Microbiology: A Systems Approach
16.4 Type III hypersensitivities: Immune Complex Reactions, page 474
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