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Mg. Q.F. QUISPE DIAZ IVAN MIGUEL

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IVAN quispe diaz

on 4 July 2014

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Transcript of Mg. Q.F. QUISPE DIAZ IVAN MIGUEL

GLUCOPEPTIDOS
VANCOMICINA: VANCO (C)
contraindicada soluciones contienenn dextrosa.
falla renal 15mg/kg DI, anúricos 1g 7-10d
obesidad (peso corporal)
TEICOPLANINA: TEICO (C)
contraindicado en la hipersensibilidad
IIa/B
VANCO:
Diarrea; clostridium difficile.
Enterocolitis estafilococica.
Infección estafilocócica MR.

IIb/B
TEICO:
Fiebre neutropénica.
Infección osea, piel.

INDICACIONES FDA
VANCO:
Hipokalemia (13%-oral)
Dolor abdominal (15%-oral)
Diarrea (9%-oral)
Nauseas (17%-oral)
Vómitos (9%-oral)

TEICO:
Rash.
RAMs COMUN
VANCO:
Aminoglicosidos; Mayor, debil, toxicidad aditiva (nefro-oto)

TEICO:
Ciprofloxacino; Moderado, rápido


INTERACCIONES FARMACOLOGICAS
ABSORCION.
Vanco: Tmax, final infusión
Teico: IM 90-92%
DISTRIBUCION.
Vanco: UPP (55%)
Teico: UPP (90 %)
METABOLISMO.
Vanco: -
Teico: -
EXCRECION
Vanco: 40-60% (s/c, 4-6h)
Teico: 42-58% renal (90-157h)

FARMACOCINETICA
Product Information: VANCOCIN(R)
oral capsules, vancomycin HCl oral capsules. ViroPharma Incorporated (per FDA), Exton, PA, 2011.

Product Information: VANCOCIN(R) oral
capsules, vancomycin HCl oral capsules. ViroPharma Incorporated (per FDA), Exton, PA, 2011.

Cimino MA, Rotstein C, Slaughter RL et al: Relationship of serum antibiotic concentrations to nephrotoxicity in cancer patients receiving concurrent aminoglycoside and vancomycin therapy. Am J Med 1987; 83:1091-1097.
Product Information: vancomycin HCl
IV injection, vancomycin HCl IV injection. APP Pharmaceuticals, LLC (per manufacturer), Schaumburg, IL, 2011.
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