Loading presentation...

Present Remotely

Send the link below via email or IM

Copy

Present to your audience

Start remote presentation

  • Invited audience members will follow you as you navigate and present
  • People invited to a presentation do not need a Prezi account
  • This link expires 10 minutes after you close the presentation
  • A maximum of 30 users can follow your presentation
  • Learn more about this feature in our knowledge base article

Do you really want to delete this prezi?

Neither you, nor the coeditors you shared it with will be able to recover it again.

DeleteCancel

Make your likes visible on Facebook?

Connect your Facebook account to Prezi and let your likes appear on your timeline.
You can change this under Settings & Account at any time.

No, thanks

gene silencing

No description
by

Rasha Hattab

on 31 January 2017

Comments (0)

Please log in to add your comment.

Report abuse

Transcript of gene silencing

What is the gene
silencing?
Prepared By: Rasha Hattab
Aims
Definition
Gene silencing
Importance
Mechanisms :
*Antisense RNA
*RNAi
May occur in 3 levels:
Why we
require silencing the expression of this gene?
Detect function of gene
Remove mutated gene
How We
remove a mutated gene?

Knock out
Knock down
Silencing &
Degradation of gene
using RNA technology
Antisence
mechanism
Silencing mechanisms
Antisense
RNAi
RNA interference
(RNAi)
RNAi
Eukaryote
Prokaryote
dsRNA
siRNA
(small
interfering)
shRNA
(short)
miRNA
(micro)
Gene silencing
Dicer enzyme
Presence of
siRNA, miRNA, shRNA
stimulate production of
risc (RNA interference silencing complex)
(protein complex)
slicer
enzyme
Argonaut enzyme
risc
bind with
mRNA
cut it
no protein production
block translation
(20nt)
Full transcript