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Vasculitis - Med IV

An overview for medical students
by

Sam Whittle

on 9 May 2010

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Transcript of Vasculitis - Med IV

Vasculitis Definition Classification Giant cell arteritis THMs 1. GCA is a medical emergency Symptoms Signs Treatment Investigations Prednisolone Low dose High dose (Polymyalgia Rheumatica) Polyarteritis nodosa (PAN) 2. Biopsy is important in GCA ...but start the prednisolone first Other small-vessel vasculitides ANCA-associated small-vessel vasculitides Anti-Neutrophil Cytoplasm Antibodies Small-vessel vasculitis "cANCA"
Antiproteinase 3 (PR3) "pANCA"
Antimyeloperoxidase (MPO) Wegener's Granulomatosis Microscopic Polyangiitis Churg-Strauss Syndrome Immune complexes (an antigen and an antibody stuck together) Other Connective Tissue Diseases Medications Chronic infections Henoch-Schonlein purpura Vasculitis mimics
(eg cholesterol
emboli) An overview 3. PMR does not need high-dose steroids 4. Small vessel vasculitis can range from mild to severe ...so be alert for organ involvement, especially kidneys
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