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Immune response IB Bio

Clonal selection, memory cells, challenge and response
by

Jasmina Milos

on 24 February 2011

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Transcript of Immune response IB Bio

Self Not self B cell Helper T cells Macrophage Non specific response Chemically recognizes antigens Starts a specific immune response by activating specific B cells The challenge and response system First reaction to something identified as "not self" Antigens Bacteria Viruses vaccines These are later identified and dealt with specifically by the B and T cells Here the challenge and response mechanism is triggered by a false challenge, causing an immune response without the risk of infection Autoimmune An autoimmune disease is a dissorder where a persons immune system recognize an element which is "self" as something which is "not self Example: Sometimes the human immune system recognizes beta cells in the pancreas as a threat and destroys them Also lupus It's never lupus. v The HIV virus targets helper T cells, eliminating the specific actions of the immune system Clonial selection Once a specific B cell is activated, it begins a series of cell divisions. This is known as cloning because all of the daughter cells can produce the same antibody. There are two types of cloned B cells: antibody-secreting plasma cells and memory cells Memory cells do not secrete antibodies during the first infection, but remain in the bloodstream, to provide true immunity to subsequent infections Principles of True Immunity There are two types of cloned B cells: Autoimmune antibody-secreting plasma cells vaccines The challange and response system Viruses B cell v An autoimmune disease is a dissorder where a persons immune system recognize an element which is "self" as something which is "not self Chemically recognizes antigens Starts a specific immune response by activating specific B cells Bacteria The HIV virus targets helper T cells, eliminating the specific actions of the immune system Clonial selection and Memory cells do not secrete antibodies during the first infection, but remain in the bloodstream, to provide true immunity to subsequent infections Example: memory cells Once a specific B cell is activated, it begins a series of cell divisions. This is known as cloning because all of the daughter cells can produce the same antibody. Non specific response Self Also lupus Antigens These are later identified and dealt with specifically by the B and T cells Macrophage Here the challenge and response mechanism is triggered by a false challenge, causing an immune response without the risk of infection Helper T cells First reaction to something identified as "not self" Sometimes the human immune system recognizes beta cells in the pancreas as a threat and destroys them It's never lupus. Principles of True Immunity Not self D Thanks for watching! v
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