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Hepatocyte - The Liver Cell

How certain organelles and cell features support the specialized function of detoxification.

Christine Isuhmazing

on 15 October 2012

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Transcript of Hepatocyte - The Liver Cell

Christine Tran
Sara Badger The Hepatocyte Hepatocyte
Sinusoidal Endothelial 4 Types of Liver Cells: The main cell for protein synthesis within the liver.
Responsible for recycling lipoproteins.
Synthesis and the breakdown of lipids from triglycerides.
Circulates protein for energy and storage.
Creates homeostasis for the body's fatty tissue deposites. The Hepatocyte An organelle that serves as the site of cellular respiration. It is located in most eukaryotic cells, but there is an elevated number in liver cells. Mitochondria An organelle containing enzymes that transfer hydrogen (H2) from various substrates to oxygen (O2) producing and then degrading hydrogen peroxide (H2O2). They exist in many cells but hepatocytes contain a large amount. Peroxisomes Smooth Endoplasmic Reticulum
Rough Endoplasmic Reticulum
Mitochondria Organelles assisting in the specialized functions of the Hepatocyte: A membrane-bound organelle that is tubular in form and lacks ribosomes. There is an abundance of Smooth ER in the liver cell. Smooth Endoplasmic Reticulum The portion of the endoplasmic reticulum in which is attached with ribosomes. Rough Endoplasmic Reticulum Main functions: Functions:
Involved in lipid synthesis.
Produce enzymes that assist in detoxification.
Host a lot of carbohydrate metabolism. (glycolysis) Functions:
Involved in the change of proteins to lipids within the cell.
Forms plasma proteins, in which are used in blood clotting and keeping the blood plasma constant. Functions:
Vital role of detoxifying
Detoxify various toxic substances that enter the blood
Converts hydrogen peroxide
Transfer hydrogen from the ethanol or alcohol molecules to oxygen
Assist in reactions that produce bile acids and cholesterol. Functions:
Metabolism of proteins, carbohydrates, and lipids.
A large portion of the process is only located in the liver cell.
Hepatocytes contain a large amount of mitochondria to keep up with the body's demand for energy and synthesis. The peroxisome organelles present in the African water mongoose cell culture Mitochondria in the human liver cell.
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