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spermatogenesis &spermiogenesis

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by

Sara Salah

on 9 November 2013

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Transcript of spermatogenesis &spermiogenesis

The birth of a baby is such a familiar event that we tend to lose sight of the wonder of this accomplishment . How does a single cell, the fertilized egg, grow to become a complex human being consisting of trillions of cells? The details of this process can fill a good-sized book.
Our intention here is simply to Outline the important events of Spermatogenesis & Spermiogenesis in details.


is the sequence of events in the seminiferous tubules of the testes that produce Male Gametes Sperm OR spermatozoa.
This Process begins around the age of 14 years (and often earlier) in males, & continues throughout life.
Every day, a healthy adult male makes about 400 million sperm.


Spermiogenesis: transformation of a spermatid to a functional sperm …

The Stepwise process of spermiogenesis consists of:
1 – Packaging of the acrosomal enzymes by the Golgi Apparatus
2 – Forming the Acrosome at the anterior end of the nucleus and positioning the centrioles at the opposite end of the nucleus
3 – Elaboration of microtubules to form the Flagellum
4 - Mitochondrial multiplication and their positioning around the Proximal portion of Flagellum
5 – Sloughing off excess cytoplasm
6 – Structure of an immature sperm released from a sustentacular cell
7 – Structure of a fully mature sperm


spermatogenesis
&
spermiogenesis

introduction
spermatogenesis
spermatogenesis
spermiogenesis
sperm
Now, let’s have a closer look at our armed – warrior …
Structure of sperm
meiosis

Gamete Formation in both sexes involves Meiosis, a unique kind of nuclear division that occurs only in gonads. Meiosis consists of two Consecutive nuclear divisions that follow one round of DNA replication.
It’s product is 4 daughter cells instead of two, each with half as many chromosomes as typical body cells.

Phases of spermatogenesis :
1- Each human Spermatogonium ( germ stem cell) gives rise to many Spermatogonia by mitosis.(2N)
2- Each Spermatogonium will then grow and develop into a Spermatocyte I(2N)
3- Each Spermatocyte I will divide by Meiosis I ( reductional meiosis) to give rise to two haploid Spermatocyte II (N)
4- Each Spermatocyte II will then divide by Meiosis II ( equational meiosis) to give rise to two Spermatids.(N)
5- the Spermatid only changes in shape and does not divide to produce a Sperm (N)
Here comes the Question :

Could the Formed Spermatid Swim all the way to the Female’s Uterus? …
How can it Survive despite the Vaginal acidic environment, as well as the thick, membranous walls of the Ovum?? …
This Long “Journey” needs Stamina, a good “Diver” & a Powerful weapon to Face the Tough “climatic conditions” ….
This exactly is the aim of Spermiogenesis …. Preparing an Army of mature Sperms capable of Invading the Ovum ….



They’re Non – replicating supporting cells (also named Sertoli cells) which extend from the Basal Lamina to the Lumen of the Tubule … How can they benefit the developing Sperm??
- They Provide Nutrients & essential developing Signals to the developing Sperm
- They Form the blood - testis barrier that prevents sperm antigens from escaping into the blood


What are Sustentacular cells??!


objectives
Describe the major Structural & Functional regions of a sperm
Define Meiosis & terms related to it.
Outline the Significance & events of Spermiogenesis
Outline events of Spermatogenesis
Know the final product of Spermatogenesis
pbl
17

4- Each Spermatocyte II will then divide by Meiosis II ( equational meiosis) to give rise to two Spermatids.(N)
3- Each Spermatocyte I will divide by Meiosis I ( reductional meiosis) to give rise to two haploid Spermatocyte II (N)
5- the Spermatid only changes in shape and does not divide to produce a Sperm (N)
2- Each Spermatogonium will then grow and develop into a Spermatocyte I(2N)
1- Each human Spermatogonium ( germ stem cell) gives rise to many Spermatogonia by mitosis.(2N)
a. The head … Contains
#NUCLEUS carrying 23 chomosomes .
# ACROSOME (tip – piece), secretes hyaluronidase & acrosin enzyme that disslolve part of the Ovum membrane to facilitate Penetration Process.

d.The Tail (Flagellum) … Consists of an axis which ends with caudal piece. It helps the sperm to move
b. The Neck … Contains two Centrioles which play an important role in the Fertilized Ovum division.
c. The middle piece … Contains Mitochonria which supply energy for the sperm movement
tutor
dr.Mohamed Hussein
Elsherbiny
desinger & speaker
Sara Salah
speakers
Aya Yousry
Aishah Umairah
Daneil Hydaiat
collecting data
Mohammad Mustaqim
Amr Mokia
Mohamed Ayman
Alyaa Romli
Farah Najiha
sayidatul sakeena
Full transcript