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Cloning presentation final version

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by

Bowen Pan

on 7 December 2012

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Transcript of Cloning presentation final version

Background photo by t.shigesa Ethical Issues Reproductive cloning Cloning Therapeutic cloning Commercial purposes



Research purposes Cloning pets Money-making schemes
Extremely high failure rate reproduction "Cloned" smoked meat "Regular" one Research 1. Cloning endangered animals

2. Cloning animal models for diseases

3. Cloning animals for drug production Cloning Endangered Animals Animal Models for Diseases Drug Production FDA (2006) Animal Welfare Beyond that... Other issues Concerns for animal welfare 1. Invasiveness for procedures -- sacrifice
2. Large number of animals required
3. Unanticipated welfare concerns -- unpredictable outcomes and failures Beyond Animal Welfare 1. Value -- concept of "telos" -- "Essence and purpose of a creature"


2. Imbalance in human-animal relationship -- cause imbalance distribution of power between human and animals More issues Morale -- some people find it inhumane -- might demolish their morale standing More issues Property -- the genetic engineering method might be considered an intellectual property Other issues Veterinarians – genetically modified animals might need a different and more specific health care and management So... what would you choose? Alyssa A. Hertal, Mengyao Wang
Wendy Pan , Zharfan Zainnudin What’s cloning? Cloning is the creation of organism that is an exact genetic copy of another. the first cloned mammal

borned in 1996

breakthrough of the year Dolly's birth Category of cloning: reproductive cloning

therapeutic cloning cloning controversies: ethics issues expense of cloning Difference with therapeutic cloning Collected and used for stem cell lines Cure potential diseases
Heart disease
Diabetes
Parkinson
Brain diseases Benefits Tissues/Cells for therapy and organ donation

Drug development and testing

Study development of diseases Lorenz Studer, 2003 Therapeutic cloning works with mice Dolly Conclusion object reproductive usage for personal usage

support Therapeutic usage

the benefits outweigh the concern of ethical issues references American Anti-vivisection Society,The U.S. Humane Society. (2008).Buyers Beware: Pet Cloning is Not for Pet Lovers.Retrieved from: http://www.nopetcloning.org/images/buyersbeware.pdf

Paterson, L., DeSousa, P., Ritchie, W., King, T., Wilmut, I..(2003),Application of reproductive biotechnology in animals: implications and potentials. Applications of reproductive cloning. Animal Reproduction Science,79,137-143. http://dx.doi.org/10.1016/S0378-4320(03)00161-1

U.S. Food and Drug Administration.(2008). Animal cloning and food safety.Retrieved from:http://www.fda.gov/downloads/ForConsumers/ConsumerUpdates/UCM203337.pdf

Hurlbut, William B. (2011). The boundaries of Humanity: The Ethics of Human – Animal Chimeras in Cloning and Stem Cell Research. A. Suaraez and J. Huarte (eds), DOI 10.1007/978-3-642-20772-3-10
Marcondes, A.(2012,Nov 6). Brazil Embarks on Cloning of Wild Animals. The Inter Press Service. Retrieved from: http://www.ipsnews.net/2012/11/brazil-embarks-on-cloning-of-wild-animals/ questions? references: Minnesota Citizens Concerned For life.(2012). Reproductive vs. ‘Therapeutic’ cloning. Retrieved from: http://www.mccl.org/reproductive-vs-therapeutic-cloning.html

Therapeutic cloning research approved. (2006,September/October).John Harvard’s Journal,80-81.Retrieved from: http://harvardmag.com/pdf/2006/09-pdfs/0906-80.pdf

Tabar, V. ,Tomishima, M., Panagiotakos, G., Wakayama, S.,...Studer, L.(2008).Therapeutic cloning in individual parkinsonian mice.Nature Medicine,14,379-381.doi:10.1038/nm1732


Rollin, Bernard E. (2012). The Perfect Storm – Genetic Engineering, Science and Ethics. Sci & Educ, DOI:10.1007/s111991-012-9511-3

Ormandy, Elisabeth H., Dale, Julie, Griffin, Gilly. (2011). Genetic engineering of animals: Ethical issues, including welfare concerns. CVJ, Vol 52.
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