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Endocrine System Overview
Transcript of Endocrine System Overview
Receptors are the lock...
Hormones are the key...
Both local and global...
- Facilitates communication
Responds to environment (both internal and external)
Helps regulate everything!
Functions via glands
Deposits into body cavities, surface of skin
More on Glands...
Manufacture secretions (2 types)...
Deposited into body cavities
Sent directly into bloodstream
Hormones released throughout...
Why don't all cells respond?
Special surface molecule
(has sensitive receptor)
Changes in cellular activity occur
Receptors can be on surface or internal...
Proteins bind to surface... (can't pass through membrane... hydrophilic, but lipophobic)
Lipids pass through membrane (lipophilic, but hydrophobic)
Autocrine vs. Paracrine
Interacts w/ cell that created it
(Cell controls its own activity)
Secretion travels short distance
to target cells
Coordinates cells within an organ
Leave body, signal cells of other organisms
Acts as "on/off" switch
Hormone prevents its own production... works in opposite direction of the disturbance
Hormone promotes the disturbance occurring to the body...
Example: Childbirth, lactation
Hormone binds to
Activated receptor sets off
that activates an enzyme
Enzyme catalyzes reactions, creating
Causes changes that
promote cellular response