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Personalized Medicine

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by

Nirushan Thanabalasingam

on 15 December 2014

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Transcript of Personalized Medicine

Personalized Medicine
Embryonic Stem Cell - derived from undifferentiated inner mass cells of human embryo
Adult Stem Cell - tissue specific undifferentiated cells that replace or repair damaged cells
Induced Pluripotent Cell - specialized cells that are reprogrammed to behave like embryonic stem cells, can specialize for different functions
Presentation
Overview
What is personalized medicine?
What are the barriers of modern medicine leading to discovering alternatives?
Major fields contributing to personalized medicine
What are the pros and cons of personalized medicine?
What in the name of Science is it?
By: Nirushan and Ramya
"Personalized medicine is an emerging practice of medicine that is tailored to the needs of a particular individual."
Why Personalized Medicine
Allows us to provide better diagnoses, safer drug prescribing, and more effective treatment
Drugs provided today are for broad populations and statistical averages, not effective for every individual
Predict susceptibility to disease and improve disease detection
Customize disease-prevention strategies
Avoid prescribing drugs with predictable side effects
"the study of genomes and the complex interactions of genes"
expected to become a primary standard in pharmaceutics
Why Not Personalized Medicine
Stem Cells
Expensive in short term
Time-consuming
Still more research needed to be done on area
Not widely available
Ethical Issues surrounding genetic testing
Genomics
Methods of Capturing Data
Genomic Applications
(It's actually useful.)
Development of Genetic Profiles
Diagnosis
Prognosis
NGS (Next-Generation
Sequencing)
Questions?
Biblography
http://ghr.nlm.nih.gov/glossary=personalizedmedicine
http://www.ontariogenomics.ca/personalized-medicine/promise-personalized-medicine
http://www.forbes.com/sites/robertpearl/2014/12/04/genomics/
"The Future of Genetics Reseach." Biology 11. McGraw-Hill Ryerson, 2010. 260 - 265. Print.
http://learn.genetics.utah.edu/content/labs/microarray/
http://technology.illumina.com/technology/next-generation-sequencing.html
http://genetichealth.jax.org/personalized-medicine/what-is/
http://www.closerlookatstemcells.org/Stem_Cell_Types.html
http://www.nih.gov/about/discovery/technology/stemcells.htm
https://www.mja.com.au/journal/2012/196/5/twenty-six-years-enteric-fever-australia-epidemiological-analysis-antibiotic
Applications of Stem Cells
Understanding disease spread
Screens for new drugs
Study neurological disorders
Unlimited supply of customized cells
Tissue Engineering
Barriers of Today's Medicine
Results from treatment of thousands of patients
Based on a "One Size Fits All" principle
Doesn't take genetic differences into account
Bacteria can become resistant to antibiotics when used in mass numbers
Full transcript