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Untitled Prezi

Genética del Asma
by

maikol arguello

on 8 August 2013

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Transcript of Untitled Prezi

Genetica del Asma
*
Maikol Arguello
Introducción
Il-5 Il-3
Il-9
Il-12 Il-13

B1/B2
Adrenergico
IgE
*
Bronconstriccion
*
Hiperreactividad
Il-4
IL-4
Anti-Inflamatorio
Basofilos
Eosinofilos
Mastocitos
Linfocitos
BLOCK
*
IL-1
*
IL-6
*
TNFa
IL-4
Producida
Arg
Glu
27
16
Asma nocturna
Hiperreactivodad
bronquial
altera
B2
Gly
16
HLA
Antigeno leucocitario Humano
Complejo de Histocompatibilidad Mayor
MHC
Cromosoma
Artropodos
Polen
Gramineas
Polen
Ambrosia
*
DRB1
*
DQB1
*
DQA1
*
DRB1
*
DRB1
Cromosoma
IgE
14
7
Cromosoma
Subunidad
Beta
sustitución
a.a.
181
mastocito
mastocito
Cromosoma
Citoquina
q- D12s97
IFN
gama
IgE
14
7
Cromosoma
Cromosoma
inmunitarias
IL-4R
Receptor
Glu
Arg
}
576
Cromosoma
Cromosoma
Cromosoma
Cromosoma
ORMDL3
Inductor Endógeno
INFLAMACIóN
*
Steven Tinoco
EPIDEMIOLOGíA
TRATAMIENTO
GRACIAS.....!
*
Agonistas Adrenergicos
*
Agonistas B2 selectivos
*
Inhibidores de Mastocitos
*
Inhibidores de Leucotrienos
*
Esteroides
*
Antagonistas Muscarinicos
° °
Cromosomas
AFECTADOS
Full transcript