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The Journey of a Red Blood Cell

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James K-D

on 28 November 2012

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Transcript of The Journey of a Red Blood Cell

Red Blood Cell THE JOURNEY OF A By James Kressinger-Dunn The Birth of a Red Blood Cell All Red blood cells begin their life in the the flexible bone marrow here Haematopoietic stem cells which reside in the medulla of the bone and have the unique ability to give rise to all of the different mature blood cell types and tissues, and are self renewing. Red blood start their life inside the bone marrow at tjhe early stage of their development they contain all organelles and a nucleus this is lost from the cell during the late erythroblast stage. The Reds blood cell only has a life span of 120 days as it does not contain a nucleus and therefore is unable to synthesise and create new cellular matter. After a erythrocyte reaches the end of its life at 120 days is broken down by the liver and spleen. 90% red blood cells are removed from the blood stream by phagocytes. The haemoglobin inside the cell is broken down into amino acid and a small majority is passed in the urine . Some Hemoglobin is transported back to the bone marrow where new haemoglobin can be created and used in the creation of new red blood cells.

The factors that increase the production of Red blood cells
Damage to bone marrow
Exposure to High altitude
Low hemoglobin levels Ann's subsequent conversation with Chris The Second Part of the journey The walls of the left ventricle then contracts moving blood up in to the aorta artery. The walls of the artey contract and relax moving blood along it the red blood cell enters the subclavian artery which runs under the clavicle {collar bone} just below the shoulder. It then progresses into the Axillary artery which is a progression from the subclavian artery which ends in pectoralis minor it then runs down the bicep and tricep before progressing itself into the branchial artey whoch runs pass the elbow here the Red blood Cell moves into veins and then into single cell thick capillaries where oxygen and nutrients from the blood can diffuse into the surrounding cells. The Journey back to the Heart The Red blood cells now lacking the oxygen moves back into the brachial vein it is then carried up into the Axillary vein then the Subclavian vein the final vein it enters is the superior venae cava this then moves the blood into the right atrium which then pumps the blood through the tricuspid valve into the right ventricle the Red blood cell is then pumped into the pulmonary Artery loads with oxygen then enters the heart via the pulmonary vein it is then pumped into the left ventricle The Journey to the Knee Fun Facts The First Part of The Journey The Red Blood Cell The red blood Cell is the most numerous cell in the human bodies blood making up 45 % they are intially produced in the bone marrow it first emerges as a reticulocyte which contains some remenants of organelles. However as the cell mature these leave the cell and it becomes a mature erythrocyte. Red Blood Cells last on average 120 days in the blood stream an when they age they are eventually removed by the liver and the spleen. A hormone called erythropoietin regulates the number of red blood cells in the blood stream this hormone is created in the kidneys and when a person develops disease of the kidneys or has one or both removed they become anemic due to the lack of this hormone. In men, there are an average of 5,200,000 RBCs per cubic millimeter and in Women their are slightly less. What makes Red Blood Cells Unique??? Red Blood Cells are biconcaved meaning that they have a high surface area to volume ratio allowing them to carry much more oxygen
As the cell matures it losses its nucleus
It contains hemoglobin which combines extremely effectively with oxygen.
Red blood cells have an amazing ability to change shape as they squeeze through the narrow capillaries in the body Every second 2.5 million RBC's are destroyed. Although this represents only 0.00001% of the total 25 trillion cells, these cells must be replaced if homeostasis is to be maintained. The production of red blood cells or Electrophoresis takes approximately 4 Days The Death of a Red Blood Cell The journey of a red blood cell around the body starts in the ventricle of the heart the strong muscles force blood up inot the pulmonary artery which carries blood away from the heart to the lungs where the red blood cell loads with oxygen which attaches itself to the hemoglobin forming oxyhaemoglobin. The Red Blood Cell then moves into the pulmonary vein and is transported back into the left aorta of the heart which then contracts forcing the blood through the bicuspid valve into the left ventricle. The Left ventricle pumps the blood into the aorta from here it joins the Renal artery on its way to the lower part of the body on its way it will pass the Kidneys and through most of the organs in the body the renal artery runs just behind the spine. It then move into the external illiac artery as it passes over the hips and quadriceps it then passes into the femoral artery and advances to the start of the popleateal artery which lies just above the Knee cap. The Journey back to the heart The Journey back to the Heart The blood then moves into the popleateal vein then as it travels up the leg it progresses to the femoral vein the blood then moves up the body into to the external illiac vein as it moves back up to the heart it enters the heart via the inferior venae cava and again enters the right atrium. And is then pumped by the left ventricle to the lungs and the process starts all over again.
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