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Down Syndrome

Genetic Disorder

Drew Leach

on 27 February 2013

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Transcript of Down Syndrome

By: Drew Leach Down Syndrome
"Trisomy 21" Affects Introduction Conclusion History and Background
Down Syndrome has always existed.

John Langdon Down published a description of this condition in 1866.

In 1959, Professor Jerome Lejeune proved that it was a chromosomal irregularity.

Caused by an extra copy of chromosome 21.

1 in 700 - 800 live births result in a child with Down Syndrome.

Children of all ethnic groups can get this disease.

Babies with mothers over the age of 35 are at a higher risk. Down Syndrome is a genetic disorder.

It affects a child before he or she is born.

Most common chromosome abnormality in humans. Treatment Citations "Children's Health." Down Syndrome (2011): n.pag.
WebMD. Web. 10 Jan 2013. <children.webmd.com/tc/down-syndrome-symptoms>. Regular medical check ups and support are the only treatments for this disorder. Jersey, Green. "When was Down's Syndrome
Discovered?." Down's Syndrome Association (2013): n.pag. Web. 10 Jan 2013. <www.downs-syndrome.org.uk/component/content/article/35-general/160-4-when-was-discovered.html>. Koprowski, Kristen, prod. Nondisjunction (Trisomy 21) - An Animated Tutorial.
2011.Film. 10 Jan2013.<www.youtube.com/watch?v=EA0qxhR2oOk&sns=em>. Down Syndrome or Tirsomy21: Chromosomal disorder. 2012. Medchrome:Medical
and Health ArticlesWeb. 10 Jan 2013. <www.medchrome.com/major/paediatrics/genetic-defects-paediatrics/down-syndrome-or-trisomy-21-chromosomal-disorder/> Down Syndrome. 2009. Medical Blog All About MedicineWeb. 10 Jan 2013.
<odlarmed.com/?p=829 Eisenberg, Arlene. "Down Syndrome." What to Expect The Toddler Years. New York:
1996 I learned that...
-Down Syndrome is caused from a problem with cell division.
-The parent gives the child 47 chromosomes instead of 46.
-The extra chromosome is a number 21 chromosome.

Below is a video representing how cell division occurs. Early education programs can help improve IQ of Down Syndrome children.

Surgery may help correct heart and digestive defects.

There is NOT a cure for Down Syndrome.
Head, nose, hands, muscle, almost every part of the body is affected.

Symptoms can be...
-physical abnormalities
*flat back of head
*wide nose
*short wide hands
*poor muscle tone
-thyroid problems
-mental retardation
-developmental delay.

88% of people live past their first year and into their mid 40's.
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