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Potential Impact of Periodontal Infections on Overall Genera

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Diana Macri

on 5 February 2018

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Transcript of Potential Impact of Periodontal Infections on Overall Genera

It begins...
Cardiovascular (Heart Disease)
walls of key arteries to the heart (coronary arteries) thicken
in response to chronic injury
sudden interruption of blood to the brain
Diabetes Mellitus
a group of disorders characterized by hyperglycemia that results from defective insulin secretion, defection insulin action, or both
Alzheimer's Disease
progressive atrophy of the cerebral cortex with a gradual loss of short-term and long-term memory
Pathologic hallmarks: amyloid plaques and neurofibrillary tangles
AD is an innate inflammatory response in an attempt to remove the amyloid deposits from the brain
genus Treponema, antigens from oral bacteria, elevated serum antibodies
Pregnancy Complications and Outcomes
Human gestation is 40 weeks; preterm- less than 37 weeks
LBW- <5.5 lbs
Potential Impact of
Infections on
Overall General Health

multifactorial disease; other factors can injure
Gram- bacteria inflammatory mediators labor
Campylobacter rectus
Prevotella intermedia
C-Reactive Protein (CRP)
a protein found in the blood that reflects the amount of inflammation in your body
Periodontitis and other sources of inflammation elevate CRP levels.
Elevated CRP is a direct risk factor for CVD
periodontal disease is the 6th most common complication of diabetes
1/3 of those with diabetes
have severe periodontitis
The Dental Hygienist's Role in the Care of a Person with Diabetes
conduct perio risk assessment
minimize risks for emergencies
detect undiagnosed/uncontrolled diabetes and refer
modify DH care plan on the basis of client needs
Worldwide incidence is expected to increase with increased
prevalence of obesity
Poorly controlled or uncontrolled: more susceptible to infections
Exposure to chronic periodontal
disease quadruples an individual's
risk of developing Alzheimer's
Pancreatic cancer-men with a history of periodontitis are 54% more likely to develop pancreatic cancer than men with healthy gingiva
Head and neck cancers-chronic periodontitis is associated with the incidence of head and neck cancers
lung cancer


Leading cause of death in the US. More than half of the deaths due to heart disease in 2009 were in men.
About 610,000 Americans die from heart disease each year—that’s 1 in every 4 deaths.
In the United States, someone has a heart attack every 43 seconds. Each minute, someone in the United States dies from a heart disease-related event.
Heart disease and stroke cost the nation an estimated $320 billion in health care costs and lost productivity in 2011 (1 in every 6 healthcare dollar)
Numerous conditions that negatively affect the heart and blood vessels; Cardio=heart, vascular= veins and arteries
Related to
Hypertension underlies most cardiovascular disease

*Periodontal interventions result in a reduction in systemic inflammation and endothelial dysfunction but there is no evidence that they prevent atherosclerotic vascular disease or modify its outcomes.*

Periodontal Disease and Atherosclerotic Vascular Disease: Does the Evidence Support an Independent Association?
Learning objectives:
Discuss the connection between periodontal disease and overall general health.
Define bacteremia and its effects on general health.
Discuss bi-directional relationship between periodontal disease and adverse pregnancy outcomes, diabetes mellitus, coronary heart disease, cerebrovascular disease, pulmonary diseases, neurologic diseases and cancer.
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