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Muscles- Sliding Filament Theory

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Michael Burke

on 27 April 2018

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Transcript of Muscles- Sliding Filament Theory

The Sliding Filament Theory
Step 2
Energized myosin heads reach up and attach to the active site on the actin.
Step 3
Myosin head pivots
Step 4
Detachment of Cross-Bridge
Step 5
Myosin Reactivation
More to know
SFT actions are synchronized but not congruent.
Step 1
Calcium is released from the SR
Binds to Troponin and moves Tropomyosin out of the way.
This exposes the active site on the actin
This forms a "Cross-Bridge"
Called the "Power Stroke"
This releases ADP and P from the myosin head
Caused by ATP binding with myosin head
ATP is broken down to ADP to provide energy to "recock"the myosin head
This process continues until calcium is actively removed
Rigor Mortis
Steps 2-5
The muscle fiber is either active or not, there is no in between
Today we will identify the steps of the Sliding Filament Theory.
We will also construct an example of the microscopic structure of muscle
Muscle Fiber
Muscle Fascicle
Blood Vessels
Step 6
If the stimulus is removed, the calcium is reabsorbed into the SR.
Full transcript