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Oxidative Phosphorylation

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Bio Prezis SPSCepiel

on 13 January 2013

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Transcript of Oxidative Phosphorylation

The 3rd and Final Stage of Cellular Respiration Oxidative Phosphorylation Oxidative Phosphorylation
2 Parts 1. Electron Transport Chain

2. Chemiosmosis Protein Complexes Protein Complexes Part 2 Where does oxidative phosphorylation
take place in the cell? MITOCHONDRIA 1. Intermembrane
space Innermitochondrial
membrane Matrix By looking at the picture above, can you identify what the yellow layers represent? A phospholipid bilayer. Where is this membrane found? In the inner membrane or cristae of the mitochondria. So how would you describe the location of the electron transport chain? The ETC is imbedded in the inner membrane
of the mitochondria. Now let's follow the path of electrons through the path shown above.
First try to describe the path with your neighbor. Electron path:
1. NADH and FADH2 bring electrons from glycolysis and the Kreb's Cycle to this path. 2. NADH and FADH2 are oxidized as they lose their
electrons to the protein complexes of electron carriers. 3. The electron carriers pass the electrons down the chain through redox reactions. 4. The electrons are eventually received
by oxygen molecules. What do you notice about the concentration of H ions on the outside of the membrane? How can the membrane maintain this concentration? The protein complexes use the energy given off by the redox reactions to pump H ions out of the membrane to set up a concentration gradient. The Gradient What is the point of this H ion gradient? The gradient stores potential energy similar to a dam. The ATP synthase harnesses this energy by allowing the H ions to flow down the gradient and activate the active sites that attach P to ADP creating ATP. This is called Chemiosmosis. Why is this process
called Oxydative Phosphorylation?
Talk to your neighbor. Energy comes from the OXIDATION reactions in the ETC and ATP are PHOSPHORYLATED by ATP synthase. Can you identify anything in this animation that is part of the mitochondria? You will get a chance at the end to try again!
Full transcript