Anti-Depression

Third Class
Doxepin
Second Class
Mono-Amine Oxidase inhibitors
First Class
Fluoxetine
(Prozac)
Anti-Depressants
Drugs
What is depression?
When you feel that you are in a bad mood and you have no desire to do any activity. The most dangerous symptom of depression is that it bushes the patient to
try to kill himself
all the time or to kill anyone.
Types of Depression
Major Depression
Persistent
Depressive Disorder
Bipolar disorder
Seasonal
Affective Disorder
Situation Depression
Atypical Depression
Postpartum Depression
Classification
of Anti-Depressants
Monoaminoxidase
Tricyclic Anti-Depressants
(Lowest side effects)
Selective Serotonin
Reuptake Inhibitors (SSRIs)
Adrenergic reuptake inhibitor (ARI)
Reboxetine
Mechanism of action of Reboxetine
Uses
1) Severe Depression
2) Panic Disorder
3) Patient that are more active and
their attention is low.
Contraindications
Side Effects
Drug interactions
Robexetine is metabolized by
CYP3A4 which is induced by
Erythromycin and inhibited by
Phenytoin.
Hydrazine group
Non-hydrazine
group
Mechanism
of Action
Uses
1) Depression
2) Panic disorders
3) Posttraumatic stress
Side Effects
Contraindications
- Not used in combination with MAO inhibitors because it causes hypertension.
- Not used in combination with selective serotonin reuptake inhibitors due to serious fatal reactions including hyperthermia.
Drug
Interactions
Uses
Side Effects
Contraindications
Drug
Interactions
Selective serotonin re-uptake inhibitors
Mechanism of Action
Side Effects
Mechanism of Action:-
Uses
Side Effects
Drug Interactions
Contraindications
Dr of lecture : Mona
Dr of lab: Nada
Khaled Mohamed (135505)
Shimaa Adel Sayed (134919)
Lamice Mohamed (130239)
Karima Ismail Kamal (134945)
Lekaa Mohamed (135085)
Amir Shebl El Sayed (131445)
GP: A