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ECSTASY

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by

Nachum Serota

on 21 October 2013

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Transcript of ECSTASY

ECSTASY: UNDER THE SURFACE
ECSTASY
Molly, XTC, Adam, Essence, Clarity, Love Drug, Hug Drug, E

Schedule I controlled Substance since 1985
Effects and "Side" Effects
MECHANISM OF ACTION

Normal Serotonin Reaction:
MDMA
3,4 methylene dioxymethamphetamine

Peacefulness
Self-Confidence
Increased Energy
Distortions in Time
Distortions in Perception
Prosocial Feelings
Addiction
Damage Neurons
Confusion
Depression
Fatigue
Sleep Problems
Paranoia
Anxiety
Muscle Tension
Teeth Clenching
Nausea
Blurred Vision
Faintness
Sweating
Increased Heart Rate
Increased Blood Pressure
Liver Damage
Taking Advantage of the Serotonin Pathway
Serotonin released into nerve synapses where the Serotonin receptors are activated and send a biochemical cascade leading to a psychological feeling of peacefulness
MDMA Reaction:
MDMA has a similar structure to the Serotonin molecule.
MDMA taken up by the transporter proteins in presynaptic cell
Synaptic concentration of Serotonin increases dramatically.
MDMA invades cell, promotes greater release of Serotonin.
Serotonin
MDMA
Serotonin Reuptake Inhibitors

(SRIs)

and

Selective Serotonin Reuptake Inhibitors
(SSRIs) are designed as

--> anti-depressants, anti-anxiety, obesity, fibromyalgia, and premature ejaculation


(RS)-1-(benzo[d][1,3]dioxol-5-yl)-N-methylpropan-2-amine
Full transcript