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Prevention of Mother-to-Child Transmission of HIV

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Caitlin Baird

on 29 March 2011

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Transcript of Prevention of Mother-to-Child Transmission of HIV

Prepartum Breastfeeding Delivery but nothing is ever simple Biology Vertical transmission of HIV can occur in one of three ways when infected maternal blood crosses the placenta this is relatively rare, and is dependent on two main factors:
maternal viral load, &
placental integrity vertical transmission of HIV can also occur during this is thought to occur in one of three ways: 1) via direct contact of the fetus with maternal blood or vaginal secretions during passage through the birth canal
2) via infected fluids from the vagina or cervix that travel upwards into the uterus during labor
3) via micro-transfusion of circulating maternal blood into fetoplacental circulation during uterine contractions the chances of this are also dependent on maternal viral load,
as well as the relative susceptibility of the fetus often, elective Caesareans are suggested. as well as during through either infected cells,
or through free-floating virus Without intervention, the rate of vertical transmission
is between 20% and 40% and over half of the children infected will die before their 2nd birthday with properly timed interventions.. the transmission rate shrinks to 2% a large part of successful intervention depends on the timely administration of ARV cocktails but successful interventions are tricky, and must always be designed around local context this has led to several innovative approaches that take into consideration institutional political social economic and cultural contexts take, for example, this project by a Cambridge PhD student structural effects, like poverty make access to interventions access to Caesareans if needed, formula...or even the clean water needed to make it like properly-timed and administered ARVS difficult to come by for many of the people who need it the most and so we have to ask ourselves Is health a right, or a privilege?
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