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Cell Membranes

All images from Wikimedia Commons, used under Creative Commons Attribution-Share Alike 3.0 unported license

Christopher Himmelheber

on 7 October 2015

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Transcript of Cell Membranes

The Cell Membrane
Fluid Mosaic Model
Phospholipid bi-layer with associated proteins
a steroid lipid
acts as a "temperature buffer" to help maintain membrane fluidity over a range of temperatures
Membrane Proteins
Various, depending on the role they play:
Integral proteins: penetrate one or both layers of the bi-layer.
Peripheral proteins: associated with the membrane, but don't penetrate the bi-layer.
The polarity of different regions of a membrane protein vary according to the role of that protein.
Many and more. Here's brief overview:
Membrane Receptors
Integral proteins that span the bi-layer with regions ("domains") that extend extra- and intra-cellularly.
Signal Transduction: The reciept of chemical messages from the environment and the relay (transduction") of those messages into the cell for response.
Integral proteins that span the bi-layer with short polysaccharide residues projecting extra-cellularly into the environment
Cell-Cell Recognition: Glycoproteins serve as an identifying marker in cellular populations (like your body).
Membrane receptors are exploited by viruses
Glycoproteins are a complication for organ transplants (why?)
Lipids with a phosphate attached to glycerol in place of a fatty acid tail.
Polar phosphate "head", nonpolar fatty acid tails.
"Amphipathic" molecule
Spontaneously organizes in the presence of water to form a bi-layer
Fluid: phospholipids are constantly moving
Membrane Phospholipids
Makes a "selectively permeable" membrane. Only small, non-polar molecules can easily move through the phosopholipid bi-layer
membrane proteins are mobile in the cell membrane:
Full transcript