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White Blood Cells Immunology Group

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by

Chevaughn Campbell

on 17 December 2012

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Transcript of White Blood Cells Immunology Group

White Blood Cells Types of White Blood Cells Leukocytes Neutrophil
Lymphocyte
Monocyte
Eosinophil
Basophil White Blood Cells are cells of the immune system involved in defending the body against both infectious disease and foreign materials. Each type of White Blood Cells
is designed to handle certain
specific types of attack or foreign cells. Neutrophil Most Abundant
Essential part of the innate immune system
First-responders of the immune system Monocyte Part of the innate immune system
Replenish resident macrophages
and dendritic cells
Response to inflammation signals Each White Blood Cell has a different level
of Abundance this allows them to work
effectively with each other
to protect the body. What are White Blood Cells ? White Blood Cells are an essential building blocks to maintaining a healthy body.

So let us get to know each part a little better. Functions Protect the body against disease and infections

Removes and destroys
bacteria
wastes
foreign substances
and other cells The formal name for process that cells like
Neutrophils go through to destroy or devour
bacteria and foreign cells

Check it Out... Phagocytosis Characteristics Microscope imaging has allowed a closer look at the how white blood cells really look like.

Neutrophils have three to five round sections called lobes that are connected by chromatin, nucleus stains dark purple/blue. 25-30% abundant in adults
Small lymphocytes 7–8 micrometer
Large lymphocytes 12–15 micrometers Lymphocytes Recognizing and deactivating
specific foreign substances called antigens

Produces to different kind of cells which help in
responding and destroying antigens or foreign cells.

T cells contain receptors on their surfaces that recognize and bind to specific antigens.
This is known as cellular immunity.

B cells secrete antibodies into the body's fluids
This is known as humoral immunity Functions Lets watch the T- cells and B cells go to work !!! Attack Antigens !!!! Lymphocytes are distinguished
by having a deeply purple stained nucleus
with relatively small amount of cytoplasm Characteristics React to the signals from innate cells
and antigen specific cells

Turns into a Macrophage
when inside a tissue

Helps T cells by breaking down pathogens to be recognized again and killed, or so that an antibody response may be mounted

Uses cytokines to alert other cells Functions The Video Shows a Macrophage ingesting bacteria.
The macrophage then releases cytokines,
chemicals that attract other
White Blood Cells to the infected area Specialized cell of the immune system
Formed in the bone marrow and spend 8 days maturing before they move into the blood vessels
Travel through the vessels for 8 to 12 hours towards destination tissues
remain for 1 to 2 weeks in destination tissue
are rarely found in 1-6% of the total white blood cells. Eosinophil Active in inflammatory responses

Participating in immediate allergic reactions

Modulates inflammatory responses

produce histaminase, and aryl suphatase B

important in killing parasitic worms Functions generally has a nucleus with two lobes and cytoplasm
large granules containing enzymes and proteins Characteristics Searching..... Still Searching.... Most uncommon White Blood Cells

Only 1% of all the White Blood Cells Basophils Secrete:

Anti-coagulant

Histamines

Serotonin

Responsible for allergic and antigen response by releasing the chemical histamine causing vasodilation Functions High Levels Basophils Levels Low Levels Infection from a virus
Inflammation is healing
Asthma
Chronic Dermatitis
Crohn’s Disease Severe allergies
Hyperthyroidism
Pregnancy Characteristics has large blue/purple granules Searching... The Lymphomaniacs THE END... Yiannis
Group Leader Laura Manouchka Allison Lindsay Chevaughn Neutrophils

http://coloncancer.about.com/od/glossary/g/neutrophils.htm
-http://www.medfriendly.com/neutrophil.html

Lymphocytes

http://thyroid.about.com/library/immune/blimm07.htm
http://dictionary.reference.com/browse/lymphocyte?s=t
https://www.google.com/imghp?hl=en&tab=wi (for images)
http://www.sciencephoto.com/media/156053/enlarge (for image)

Monocyte/ Macrophage

http://www.rndsystems.com/molecule_group.aspx?g=692&r=4

Eosinophil

http://www.histology.leeds.ac.uk/blood/blood_wbc.php http://www.cincinnatichildrens.org/service/c/eosinophilic-disorders/conditions/eosinophil/ http://www.medfriendly.com/eosinophil.html

Basophils
http://www.funsci.com/fun3_en/blood/blood.htm#21
http://www.medfriendly.com/basophil.html

Videos
Nucleusinc.com References: Searching...
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