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Leukemia Awareness

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by

Rahi Patel

on 29 January 2014

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Transcript of Leukemia Awareness

Leukemia Awareness
What is it?
Types of Leukemia
The four main types of leukemia are:
A
cute
L
ymphoblastic
L
eukemia, or
ALL
.
A
cute
M
yelogenous
L
eukemia, or
AML
.
C
hronic
L
ymphocytic
L
eukemia, or
CLL
.
C
hronic
M
yelogenous
L
eukemia, or
CML
.
Bibliography
Chemotherapy, Nausea, Vomiting, Fatigue, Diarrhea, Hair loss, Mouth Sores, Neuropathy, Chemobrain |
CancerCare
. (2012, March 1). Retrieved January 18, 2014, from http://www.cancercare.org/publications/24-understanding_and_managing_chemotherapy_side_effects#possible-side-effects
Leukemia- Symptoms, Types, Causes, Diagnoisis and Treatment Options for Leukemia
. (2010,
December 17). Retrieved January 15, 2014, from http://www.webmd.com/cancer/tc/leukemia-topic-overview
Leukemia Treatment at Mayo Clinic - Diseases and Conditions - Mayo Clinic
. (2013, October 3). Retrieved
January 20, 2014, from http://www.mayoclinic.org/diseases-conditions/leukemia/basics/treatment/con-20024914
Radiation Therapy and You - National Cancer Institute
. (2007, April 20). Retrieved January 16, 2014, from
http://www.cancer.gov/cancertopics/coping/radiation-therapy-and-you/page6
Schoenstadt, A. (2013, June 14).
Biological Therapy for Leukemia
. Retrieved January 19, 2014, from
http://leukemia.emedtv.com/leukemia/biological-therapy-for-leukemia.html
Side effects of bone marrow and stem cell transplants : Cancer Research UK : CancerHelp UK
. (2013, July
12). Retrieved January 21, 2014, from http://www.cancerresearchuk.org/cancer-help/about-cancer/treatment/transplant/side-effects-of-bone-marrow-and-stem-cell-transplants
Side effects of targeted therapy drugs
. (2013, July 12). Retrieved January 17, 2014, from http://
www.cancer.org/treatment/treatmentsandsideeffects/treatmenttypes/targetedtherapy/targeted-therapy-side-effects
Swierzewski III, S. J. (2011, May 24).
Leukemia Facts & Figures - Leukemia - HealthCommunities.com
.
Retrieved January 22, 2014, from http://www.healthcommunities.com/leukemia/facts-figures.shtml
How does it work?
The bone marrow starts to make
abnormal white blood cells
, called
leukemia cells
.
These leukemia cells grow faster than normal cells, and they do not stop growing when they should.
What Can Happen?
Leukemia cells can crowd out the normal blood cells
Serious problems can arise:
Anemia
Bleeding
Infections
Can spread to:
Lymph nodes and other organs
Chronic Lymphocytic Leukemia (CLL)
Gets worse slowly
Occurs more frequently in
adults in their 60s
More common in men and is rarely seen in children
Symptoms include:
weakness and fatigue
fever and night sweats
poor appetite
weight loss
spleen and lymph glands may become swollen and painful
more likely to get infections
Chronic Myelogenous Leukemia (CML)
Gets worse slowly
More common in men than in women
Occurs more frequently in
adults in their 50s
and is rarely seen in children
Most people have a gene mutation called the
Philadelphia Chromosome
Symptoms include:
weakness and fatigue
fever and night sweats
poor appetite
weight loss
spleen may become swollen and painful
Classified into three distinct phases:
chronic phase
accelerated phase
blast crisis phase
Leukemia is cancer of the
blood cells
. It starts in the
bone marrow
, or the
soft tissue
inside most bone. This is where blood cells are made.

Healthy bone marrow makes:
White Blood Cells
, which help the body fight infection.
Red Blood Cells
, which carry oxygen throughout the body.
Platelets
, which help the blood clot.

Target Population:
Children younger than 10
Adults 40-70 years old
Acute Lymphoblastic Leukemia (ALL)
Gets worse quickly
Most common type of childhood leukemia
Occurs in children
ages 2 through 5 years

Also occurs in adults
Most successfully treated type of childhood leukemia
Symptoms include:
fever
weakness or feeling tired
bruising or bleeding easily
pinpoint spots under the skin from bleeding
bone pain
loss of appetite
Acute Myelogenous Leukemia (AML)
Gets worse quickly
More common in men than in women
Also affects children
Increases with age
Acquired rather than inherited
May be caused by:
High doses of
radiation
Exposure to the chemical
benzene
Smoking and other
tobacco use
Chemotherapy
More common in children with
Down syndrome
or other
genetic conditions
Symptoms include:
Weakness and fatigue
fever and night sweats
pain or feeling of fullness below the ribs
Adults may have unexplained weight loss
Children also may have easy bruising or bleeding
pinpoint spots under the skin from bleeding
painless blue or purple lumps
bone or joint pain
The Differences?
Acute
or
Chronic
Acute
leukemia gets worse very fast and may make you feel sick right away
Chronic
leukemia gets worse slowly and may not cause symptoms for years

Lymphocytic
or
myelogenous

Lymphocytic
(or lymphoblastic) leukemia affects white blood cells called
lymphocytes
.
Myelogenous
leukemia affects white blood cells called
myelocytes
.
4 Types of Leukemia
Risk Factors & Symptoms
Risk Factors:
Being exposed to large amounts of
radiation
.
Being exposed to certain chemicals at work, such as
benzene
.
You had some types of
chemotherapy
to treat another cancer.
You have
Down syndrome
or some other
genetic problems
.
You
smoke
.

Symptoms:
Fever and night
sweats
.
Headaches
.
Bruising
or
bleeding
easily.
Bone or joint
pain
.
A swollen or painful belly from an
enlarged spleen
.
Swollen lymph nodes
in the armpit, neck, or groin.
Getting a lot of
infections
.
Feeling
very tired
or weak.
Losing weight
and not feeling hungry.
Treatment
Treatment for leukemia depends on many factors. The doctor determines the leukemia treatment options based on one's age and overall health, the type of leukemia one has, and whether it has spread to other parts of one's body.
Common treatments used to fight leukemia include:
Chemotherapy
Biological Therapy
Targeted Therapy
Radiation Therapy
Stem Cell Transplant
Radiation Therapy
Uses X-rays or other high-energy beams
May be used to prepare for a stem cell transplant.

Side Effects:
Diarrhea
Hair loss in the treatment area
Mouth problems
Nausea and vomiting
Swelling
Trouble swallowing
Urinary and bladder problems
Targeted Therapy
Uses drugs that attack specific vulnerabilities
Imatinib (Gleevec) stops action of a protein within leukemia cells of people with Chronic Myelogenous Leukemia

Side Effects:
Skin problems
High blood pressure
Problems with bleeding or clotting
Problems with wound healing
Chemotherapy
Major form of treatment
Treatment uses chemicals to kill leukemia cells
One may receive a single drug or a combination of drugs
May come in a pill form, or may be injected directly into a vein

Side Effects:
Nausea and Vomiting
Fatigue
Mouth Sores
Nerve Damage
Diarrhea/Constipation
Hair Loss
Biological Therapy
Helps immune system recognize and attack leukemia cells

Side Effects:
Rashes or swelling where the biological therapy is injected
Flu-like symptoms
5 Types of Treatment
Stem Cell Transplant
Replaces diseased bone marrow with healthy bone marrow.
One may receive stem cells from a donor, or in some cases one may be able to use own stem cells
Very similar to bone marrow transplant.

Side Effects:
Risk of infection
Anemia
Risk of bleeding
Sickness and diarrhea
Difficulty eating and drinking
Feeling tired and run down
By Rahi Patel
Full transcript