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Artemisinin

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clare cuthbert

on 6 November 2013

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Transcript of Artemisinin

Artemisinin
General Information
IUPAC Name: (4S,5R,8S,9R,12S,13R)-1,5,9-Trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-one

CAS Registry Number: 693968-64-9
Where it is found
There are many places where this substance is not found. It is NOT found naturally in the body, it is NOT found in personal care products, it is NOT used in pesticides, NOT found in carbonated drinks, and it is NOT used as an acid in optometry.




References
Chirality
Artemisinin is a chiral molecule with seven chiral centers. this means Artemisinin could have 128 different stereoisomers.
Medicinal properties
Artemisinin is primarily used as an antimalarial drug, and because of this it has anti inflammatory properties. However,there has also been studies into how it also targets iron cells to treat cancer in animals.
Artemisinin is not an anthestetic, nor an alkaloid. It has no addictive properites in small doses and not known to be toxic. however in large doses, there are cardiovascuar disturbances.


Where is it actually found
Artemisinin is a natural drug derived from the green plant Artemisia annua but is converted into a white powdery substance or white pills for medicinal use.
Structure
Structure Information
Has bicyclic rings
Has heterocyclic rings
NO three or four membered rings

IR Spectra information
Artemisinin has a broad peak at about 3600 cm-1
Artemisinin also contains oxygen and therefore has a strong peak at about 1600 to 1800 cm-1


Physical and Chemical Properties
Molecular formula: C15H22O5

Molar Mass: 282.3322

Melting point: 156-157°C

Boiling point: 389.9°C at 760 mmHg

Because of boiling and melting point, Artemisinin is solid at room temp (25°C)


ChemSpider.Artemisinin: structure.http://www.chemspider.com/Chemical-Structure.62060.html (accessed Oct 30, 2013).

Online Drug Information System: Artemisinin. http://druginfosys.com/Drug.aspx?drugCode=1429&drugName=&type=7 (accessed Oct 30, 2013).

Alibaba.com: Natural Artemisinin in Bulk. http://www.alibaba.com/product-gs/855984794/Pure_Natural_Artemisinin_in_bulk.html (accessed Oct 30, 2013).

Supplierlist.com, Global trade from China: Artemisinin. http://www.supplierlist.com/product_view/yql602/231402/101030/Artemisinin.htm (accessed Oct 30, 2013).




Plant derivative
Powder derivative for
medicine
Academia.edu: Anthony Melvin Crasto Ph.D presents Artemisinin. http://www.academia.edu/1746106/Anthony_Melvin_Crasto_Ph.D_presents_Artemisinin (accessed Oct 30, 2013).

Artemala.com: Artemisinin. http://www.artemala.com/pd-9770-artemisinin.html (accessed Oct 30,2013),

Chemicalize.org, Properties veiwer: Qinghaosu. http://www.chemicalize.org/structure/#!mol=Qinghaosu (accessed Oct 30, 2013).


LookChem, product search: Artemisinin. http://www.lookchem.com/Artemisinin/ (accessed Oct 30, 2013).

Chemical book, product; artemisinin.http://www.chemicalbook.com/ChemicalProductProperty_US_CB3387975.aspx (accessed Oct 30, 2013).

MarvinSketch, version 6.1.3; ChemAxon ltd. product (accessed Oct 5, 2013)
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