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Drugs

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by

Harvey Buckle

on 5 September 2017

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Transcript of Drugs

Aim
To know the:

Use
Origin
Administration
R & D of drugs

Starter
What do they make?
Drugs
1. Alter mood
2. Alter Psychological state
3. Alter incoming sensation
Drugs
5th August 2017
Adinistration
1. Into skin injection
2. Into skin fat injection
3. Orally
4. Nebuliser'
5. Rectally
6. Intramuscular injection
7. Topically

R & D
1. Determine structure and manufacturing process
2. Test on animals for the Therapeutic index = LD 50 / ED 50
3. LD = Kill animals but toxic in humans
4. Low TI = careful!!
5. Then test on humans, PLACEBO
6. Side effects , risk to benefit ratio determined
7. Tolerance, dependance = LD 50
8. Further clinical trials...then increasingly wider use.
9. Approval

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