Drugs

R & D

1. Determine structure and manufacturing process

2. Test on animals for the Therapeutic index = LD 50 / ED 50

3. LD = Kill animals but toxic in humans

4. Low TI = careful!!

5. Then test on humans, PLACEBO

6. Side effects , risk to benefit ratio determined

7. Tolerance, dependance = LD 50

8. Further clinical trials...then increasingly wider use.

9. Approval

Adinistration

1. Into skin injection

2. Into skin fat injection

3. Orally

4. Nebuliser'

5. Rectally

6. Intramuscular injection

7. Topically

Starter

What do they make?

Aim

To know the:

Use

Origin

Administration

R & D of drugs

Drugs

Drugs

1. Alter mood

2. Alter Psychological state

3. Alter incoming sensation

5th August 2017