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CKD Effect on Body Systems

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Ruth Mawyer

on 14 March 2013

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Transcript of CKD Effect on Body Systems

Chronic Kidney Disease (CKD) Effect on Body Systems Body System effects Systems Neurologic Hematologic Gastrointestinal Cardiovascular Creatinine & Urea clearance Cardiopulmonary Proteinuria, dyslipidemia
& increased Angiotenson II Common Signs & Symptoms Table 29-14 Symptoms Symptoms Page 757 Not apparent until function declines to
25 % of normal Page 758 Proteinuria adds to tubulointerstitial injury by building up in interstitial space, promotes inflammation, and fibrosis. Loss of muscle mass.
Dyslipidemia: altered fat metabolism.
Angiotenson II leads to increased glomerular hypertension and hyperfiltration.
Treatment involves dietary restriction of phospates, potassium and proteins. GFR falls and

plasma creatinine concentration increases Pulmonary edema

Kussmaul respirations L ventricular hypertrophy
ischemic heart disease
dysrhythmias (HYPERKALEMIA)
accel atherosclerosis
pericarditis with fever
chest pain
friction rub Confusion
peripheral neuropathy
loss of motor coordination
coma with advanced uremia Anemia Anorexia
pancreatitis associated with End stage renal disease Systemic Effects of Chronic Kidney Failure Skeletal:
Spontaneous fracture, bone pain &
deformities. Requires vitamin D supplementation. Hypocalcemia occurs due to reduced renal production of Vitamin D and hyperparathyroidism. Integumentary pruritis
abnormal pigmentation IMMUNOLOGIC Increased risk of infection and cancer Erythropoietin may need to be given due to reduction in renal production to induce bones to produce RBCs. Endocrine and Reproductive Decrease in sex steroids.
pregancy dsyfunction http://medgadget.com/about-us Transplant Dialysis
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