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3.06 Mutations:

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Mckenna Benjamin

on 26 February 2014

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Transcript of 3.06 Mutations:

3.06 Mutations:
Analyze a women's risk of dying of cancer if she carries a mutated BRC1 gene:
A women's risk of dying of cancer is she carries a mutated BRC1 gene are higher than if she carries a BRC2 gene, this is if she inherits a harmful mutation in the BRC1 gene. In 2007 there were 89 patients for BRC1 with 16 deaths, totaling 18 percent of the 89 died.
How do heredity and inheritance relate to the data presented in these charts?
Hereditary and inheritance relate to this chart because all the women that were studied in the chart had family history of breast cancer, meaning they most likely inherited the cancer through genes that were passed on from a on of their family members.
What does the age of diagnosis tell you about the mutation?
The average age of diagnosis is found between the ages of 40 and 50, this tells me that this type of cancer is more commonly diagnosed between these ages.
Which appears to be more dangerous: the BRC1 or BRC2 mutation?
The BRC1 mutation appears to be more dangerous because of the percentage of deaths being 18, compared to the percentage of deaths with BRC1 being 2.8 percent.
Describe how mutations lead to genetic variation:
Mutations are changes in DNA which can effect the Genetic variation because genetic variation controls the variety of genes in the population of organisms, providing genetic material for the natural selection.
Explain how breast-cancer genes are still present in the population, despite cancer-related surgeries and death:
What data would you need to see in order to draw conclusions about the effectiveness of preventive surgeries?
Breast cancer is hereditary, meaning it can be passed on through people in a family. If someone does not realize they have cancer and therefore does not catch the signs and symptoms before it's too late then the person might have kids, spreading the gene onto their offspring, this is how breast-cancer genes are still present in the population.
You would need to do lots of accurate research, you would need to see the outcome of many different peoples results to these preventative surgeries and compare these results, then go onto deciding if these surgeries were effective or not at preventing cancer.
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