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Transcript of Renal Diseases
of the Kidney Simple Renal Cyst Common finding among 25% adults age 40 and above
50% adults age 50 and above do not cause any symptoms nor harm the kidneys Discovered incidentally
when diagnostic tests are done for other reasons
common postmortem findings without clinical significance Usually Small sac located in the kidney
Commonly 1-5cm and may reach 10 cm in size
Thin Walled / Translucent
Fluid Filled (clear)
No divisions or septa
No calcification or solid components
Sooth contour and are almost always avascular
Lined by a glistening smooth membrane these membranes are composed of a single layer of cuboidal or flattened cuboidal epithelium, which in many instances may be completely atrophic Benign and Rarely Problematic Clinical Manifestations usually do not cause symptoms can occur between the ribs and hips when cysts enlarge and press on other organs
when cyst is infected
ruptured cyst Pain
Fever & Tenderness
Hematuria Confirmatory Diagnostic Tests: Renal UTZ
MRI Follow up check-up after Enlarged Obstruction to normal urinary flow Surgery (Sclerotherapy) 6-12 months Polycystic Renal
Disease Genetic disorder characterized by the growth of numerous cysts in the kidneys Estimated 12.5 million people worldwide are affected with PKD
Affects all races, ethnic groups regardless of age and sex
Its incidence is more common than Muscular Dystrophy, Down Syndrome and Cystic Fibrosis COMBINED. Two major inherited forms of PKD I. Autosomal dominant PKD
the most common inherited form.
Symptoms usually develop between the ages of 30 and 40, but they can begin earlier, even in childhood.
About 90 percent of all PKD cases are autosomal dominant PKD. Adult Polycystic Kidney Disease II. Autosomal recessive PKD
Rare inherited form.
Symptoms of autosomal recessive PKD begin in the earliest months of life, even in the womb.
Infantile PKD usually bilaterally enlarged and may achieve enormous sizes
weighs up to 4 kg
external surface is compose of a mass of cysts up to 3-4 cm in diameter with no parenchyma
cysts filled with turbid red to brown, sometimes hemorrhagic fluid
cysts arise from the tubules throughout the nephron Autosomal Dominant PKD (Adult) Autosomal Recessive PDK Kidneys are enlarged and have a smooth external appearance
on cut section, numerous small cysts in the cortex and medulla give the kidney a spongelike apperance. Autosomal Recessive PDK Polycystic kidney disease symptoms may include:High blood pressureBack or side painHeadacheIncrease in the size of your abdomenBlood in your urineFrequent urinationKidney stonesKidney failureUrinary tract or kidney infections Treating polycystic kidney disease involves supportive interventions with the signs, symptoms and complications of PKD.