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Nuclear Chemistry in Conjuction with Cancer Patients
Transcript of Nuclear Chemistry in Conjuction with Cancer Patients
They bind to cancer cells, making them more visible to the immune system, which now attaks the unwanted cells.
The antibodies stop the growth signals sent by the cancer cells by blocking the receptors.
Tumors attract blood vessels in order to attain an oxygen and nutrient supply. Monoclonal antibodies block the signals sent by the cells that attract the blood supply. Iodine-131  This isotope is used commonly with thyroid cancer because thyroid cells naturally absorb the iodine. Iodine-131 decays via beta radiation and has a half-life of about 8 days. Samarium-153  This radioactive isotope is used in conjunction with lexidronam; it comes in the form of an injection. The formula is . The samarium has a half-life of 46.3 hours and decays via beta radiation. Strontium-89  This drug is called QUADRAMET. In this case, the radioactive isotope of strontium is bonded to a chloride ion, in a drug called Metastron, which is intravenously dosed. It decays via beta radiation. It has a half-life of 50.5 days. Both Quadramet and Mestastron are palliative drugs, meaning they aren't cures, they just lessen the pain. They are used on patients whose cancers have matastasised to the bone.  Iodine-131 is bonded to tositumomab in a drug called Bexxar, administered in an injection. Tositumomab is a monoclonal antibody composed of various amino acids. It is a matter of weighing risks and benefits  You may be thinking, what's the catch? Unfortunately, radiation therapy doesn't only kill cancer cells, it also kills normal tissue. There is a long list of side effects, some of which are:
decreased blood cell count
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