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Heterochromia Iridis

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Kayla Banks

on 27 May 2011

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Transcript of Heterochromia Iridis

Heterochromia Iridis Heterochromia Iridis is a Latin name which translates directly to "different coloured irises". There are two types of Heterochromia Iridis ... Complete Heterochromia,
where the irises are two different colors. http://dermatlas.med.jhmi.edu/derm/display.cfm?ImageID=982932287 Partial or Sectoral Heterochromia, where one iris is two different colours. http://taggedwiki.zubiaga.org/new_content/797af787339ebec01bb3a9efd62bd3ac Heterochromia at birth is inherited as an autosomal dominant trait.
This means that only one abnormal gene is needed from one parent in
order for the child to develop the condition. Melanocytes are the cells in which melanin, the pigment which determines your eye colour, is made and transported throughout the body. If the travel of these cells is interrupted, and they do not make it to the correct parts of the eye, there will be a lack of pigment. Different amounts of melanin in the eye will result in different iris colours, with blue being the colour which results with the least amount of pigment. This can happen due to a variety of conditions and syndromes including ... Waardenburg Syndrome A mutation of certain genes which causes the melanocytes to get lost on their way to the eye, causing one eye to have less pigment. Ocular Melanosis An eye disease which affects 1 in 5000 people. It is caused by an increase of melanocytes in the iris, resulting with a darker pigmentation in that eye. Heterochromia which happens later in life can be caused by injury to the eye, inflammation and increased pressure within the eye, the use of certain eyedrops, and ocular tumors. As Heterochromia Iridis is a visible condition, it is unknown who discovered it and when. One of the first documented cases of Heterochromia was Anastasius I, a Roman emperor from 491 to 518. He had one black eye and one blue eye, and because of this he was nicknamed "Dicorus" meaning "Two-pupiled." According to the Office of Rare Diseases, Heterochromia Iridis is listed as a "rare disease", which means it affects less than 200,000 of the US population. Those with albinism, piebaldism (partial albinism), and incontinentia pigmenti (hypopigmentation) are most prone to developing the disease. Currently, there are no treatments or cures for Heterochromia. Although this disease is not harmful and only affects the colour of the iris, some people can be very embarrased by it. In cases such as this, the use of coloured contacts to change the eye's colour is advised. http://www.gregodonnell.com.au/contactlenses/coloured/ Famous people who have either complete or sectoral Heterochromia Iridis include ... Tim McIlrath
Lead singer of the American band Rise Against, has complete heterochromia with one brown eye and one blue eye. Christopher Walken
An American actor in movies such as Sleepy Hollow, Pulp Fiction and Hairspray. Has Sectoral Heterochromia in both eyes, with blue eyes with a green inner ring. Michael Flatley
An Irish-American river dancer and choreographer who choreographed the famous "Lord of the Dance" Irish dance show. He has complete Heterochromia with one blue eye and one grey-green eye. There are many online support groups for those who are affected by Heterochromia Iridis. Two of the most visited online support groups/discussions are www.experienceproject.com and www.inspire.com. Bibliography: http://www.thetech.org/genetics/ask.php?id=226 en.wikipedia.org/wiki/Ocular_melanosis http://www.medical-answers.org/hd/index.php?t=Heterochromia+iridis http://www.kosmix.com/topic/heterochromia/overview/adam20?fdid=Adamv2_003319&section=Full_Article http://en.wikipedia.org/wiki/Heterochromia_iridum http://news.softpedia.com/news/One-Blue-Eye-One-Brown-Eye-The-Mysterious-Disease-67681.shtml http://www.wrongdiagnosis.com/h/heterochromia_iridis/ By: Kayla Banks
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